The Proinflammatory Secretome of Senescent Cells Can Be Controlled by a HIF2A-Dependent Upregulation and a FURIN-Dependent Cleavage of the ANGPTL4 Secreted Factor.
衰老细胞的促炎分泌组可通过 HIF2A 依赖性上调和 FURIN 依赖性切割 ANGPTL4 分泌因子来控制。
期刊:Aging Cell
影响因子:7.1
doi:10.1111/acel.70307
Makulyte Gabriela, Safwan-Zaiter Hasan, Goehrig Delphine, Huna Anda, Mangelinck Adèle, Mikawa Takumi, Palazzo Alberta, Moudombi Lyvia, Medard Jean-Jacques, Chanal Marie, Lecot Pacôme, Michallet Marie-Cécile, Gavard Julie, Adnot Serge, Dubus Pierre, Kondoh Hiroshi, Mann Carl, Tan Nguan Soon, Bertolino Philippe, Flaman Jean-Michel, Bernard David