Ducho相关文献与解析，生知库 | 链接生命科学的每一步

Berida, Tomayo; Huang, Tzu-Yu; Weck, Stefanie C; Lutz, Marcel; McKee, Samuel R; Kagerah, Nathalie; Manning, Destinee L; Jahan, Mohamed E; Mishra, Sushil; Herrmann, Jennifer; Müller, Rolf; Doerksen, Robert J; Stallings, Christina L; Ducho, Christian; Roy, Sudeshna

微生物学

发表日期：2025

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Getting the Numbers Right in Medicinal Chemistry

药物化学中的正确计算

期刊:ChemMedChem

影响因子:3.4

doi:10.1002/cmdc.202400620

Ducho, Christian

发表日期：2025

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Inhibitors of the Elastase LasB for the Treatment of Pseudomonas aeruginosa Lung Infections

用于治疗铜绿假单胞菌肺部感染的弹性蛋白酶 LasB 抑制剂

期刊:ACS Central Science

影响因子:10.4

doi:10.1021/acscentsci.3c01102

Konstantinović, Jelena; Kany, Andreas M; Alhayek, Alaa; Abdelsamie, Ahmed S; Sikandar, Asfandyar; Voos, Katrin; Yao, Yiwen; Andreas, Anastasia; Shafiei, Roya; Loretz, Brigitta; Schönauer, Esther; Bals, Robert; Brandstetter, Hans; Hartmann, Rolf W; Ducho, Christian; Lehr, Claus-Michael; Beisswenger, Christoph; Müller, Rolf; Rox, Katharina; Haupenthal, Jörg; Hirsch, Anna K H

炎症/感染

发表日期：2023

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Discovery, Synthesis, and Optimization of 1,2,4-Triazolyl Pyridines Targeting Mycobacterium tuberculosis.

针对结核分枝杆菌的 1,2,4-三唑基吡啶的发现、合成和优化

期刊:ACS Infectious Diseases

影响因子:3.8

doi:10.1021/acsinfecdis.3c00341

Berida Tomayo, McKee Samuel R, Chatterjee Shamba, Manning Destinee L, Li Wei, Pandey Pankaj, Tripathi Siddharth Kaushal, Mreyoud Yassin, Smirnov Asya, Doerksen Robert J, Jackson Mary, Ducho Christian, Stallings Christina L, Roy Sudeshna

微生物学

发表日期：2023

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Identification and Biochemical Characterization of Pyrrolidinediones as Novel Inhibitors of the Bacterial Enzyme MurA

吡咯烷二酮作为细菌酶 MurA 新型抑制剂的鉴定和生化特性

期刊:Journal of Medicinal Chemistry

影响因子:6.8

doi:10.1021/acs.jmedchem.2c01275

Reem K Fathalla, Wolfgang Fröhner, Chantal D Bader, Patrick D Fischer, Charlotte Dahlem, Deep Chatterjee, Sebastian Mathea, Alexandra K Kiemer, Haribabu Arthanari, Rolf Müller, Mohammad Abdel-Halim, Christian Ducho, Matthias Engel

微生物学

发表日期：2022

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Inhibition of Collagenase Q1 of Bacillus cereus as a Novel Antivirulence Strategy for the Treatment of Skin-Wound Infections

抑制蜡样芽孢杆菌胶原酶 Q1 作为治疗皮肤伤口感染的新型抗毒力策略

期刊:Advanced Therapeutics

影响因子:

doi:10.1002/adtp.202100222

Alaa Alhayek, Essak S Khan, Esther Schönauer, Tobias Däinghaus, Roya Shafiei, Katrin Voos, Mitchell K L Han, Christian Ducho, Gernot Posselt, Silja Wessler, Hans Brandstetter, Jörg Haupenthal, Aránzazu Del Campo, Anna K H Hirsch

微生物学

发表日期：2022

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The rhythm of effective entrepreneurs’ decision-making process. The pathways of alertness scanning and search and cognitive style. A mediation model

高效企业家决策过程的节奏。警觉扫描和搜索路径以及认知风格。一种中介模型

期刊:Nanoscale Research Letters

影响因子:

doi:10.1186/1556-276X-7-332

Klapetek, Petr; Valtr, Miroslav; Ducho 328, Václav; Sobota, Jaroslav; Sassetti, Sara; Cavaliere, Vincenzo; Lombardi, Sara

神经科学

发表日期：2022

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Enzymatic C(β)-H Functionalization of l-Arg and l-Leu in Nonribosomally Derived Peptidyl Natural Products: A Tale of Two Oxidoreductases

非核糖体衍生肽类天然产物中l-Arg和l-Leu的酶促C(β)-H官能化：两种氧化还原酶的故事

期刊:Journal of the American Chemical Society

影响因子:15.6

doi:10.1021/jacs.1c08177

Cui, Zheng; Nguyen, Han; Bhardwaj, Minakshi; Wang, Xiachang; Büschleb, Martin; Lemke, Anke; Schütz, Christian; Rohrbacher, Christian; Junghanns, Pierre; Koppermann, Stefan; Ducho, Christian; Thorson, Jon S; Van Lanen, Steven G

发表日期：2021

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A biphenyl inhibitor of eIF4E targeting an internal binding site enables the design of cell-permeable PROTAC-degraders

一种靶向eIF4E内部结合位点的联苯抑制剂可用于设计细胞可渗透的PROTAC降解剂。

期刊:European Journal of Medicinal Chemistry

影响因子:5.9

doi:10.1016/j.ejmech.2021.113435

Fischer, Patrick D; Papadopoulos, Evangelos; Dempersmier, Jon M; Wang, Zi-Fu; Nowak, Radosław P; Donovan, Katherine A; Kalabathula, Joann; Gorgulla, Christoph; Junghanns, Pierre P M; Kabha, Eihab; Dimitrakakis, Nikolaos; Petrov, Ognyan I; Mitsiades, Constantine; Ducho, Christian; Gelev, Vladimir; Fischer, Eric S; Wagner, Gerhard; Arthanari, Haribabu

N-Aryl mercaptoacetamides as potential multi-target inhibitors of metallo-β-lactamases (MBLs) and the virulence factor LasB from Pseudomonas aeruginosa

N-芳基巯基乙酰胺作为金属-β-内酰胺酶 (MBL) 和铜绿假单胞菌毒力因子 LasB 的潜在多靶点抑制剂

期刊:RSC Medicinal Chemistry

影响因子:4.1

doi:10.1039/d1md00187f

Samir Yahiaoui, Katrin Voos, Jörg Haupenthal, Thomas A Wichelhaus, Denia Frank, Lilia Weizel, Marco Rotter, Steffen Brunst, Jan S Kramer, Ewgenij Proschak, Christian Ducho, Anna K H Hirsch

信号转导

发表日期：2021

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1,2,4-Triazole-Based First-in-Class Non-Nucleoside Inhibitors of the Bacterial Enzyme MraY

基于1,2,4-三唑的首创非核苷类细菌酶MraY抑制剂

Getting the Numbers Right in Medicinal Chemistry

药物化学中的正确计算

Inhibitors of the Elastase LasB for the Treatment of Pseudomonas aeruginosa Lung Infections

用于治疗铜绿假单胞菌肺部感染的弹性蛋白酶 LasB 抑制剂

Discovery, Synthesis, and Optimization of 1,2,4-Triazolyl Pyridines Targeting Mycobacterium tuberculosis.

针对结核分枝杆菌的 1,2,4-三唑基吡啶的发现、合成和优化

Identification and Biochemical Characterization of Pyrrolidinediones as Novel Inhibitors of the Bacterial Enzyme MurA

吡咯烷二酮作为细菌酶 MurA 新型抑制剂的鉴定和生化特性

Inhibition of Collagenase Q1 of Bacillus cereus as a Novel Antivirulence Strategy for the Treatment of Skin-Wound Infections

抑制蜡样芽孢杆菌胶原酶 Q1 作为治疗皮肤伤口感染的新型抗毒力策略

The rhythm of effective entrepreneurs’ decision-making process. The pathways of alertness scanning and search and cognitive style. A mediation model

高效企业家决策过程的节奏。警觉扫描和搜索路径以及认知风格。一种中介模型

Enzymatic C(β)-H Functionalization of l-Arg and l-Leu in Nonribosomally Derived Peptidyl Natural Products: A Tale of Two Oxidoreductases

非核糖体衍生肽类天然产物中l-Arg和l-Leu的酶促C(β)-H官能化：两种氧化还原酶的故事

A biphenyl inhibitor of eIF4E targeting an internal binding site enables the design of cell-permeable PROTAC-degraders

一种靶向eIF4E内部结合位点的联苯抑制剂可用于设计细胞可渗透的PROTAC降解剂。

N-Aryl mercaptoacetamides as potential multi-target inhibitors of metallo-β-lactamases (MBLs) and the virulence factor LasB from Pseudomonas aeruginosa

N-芳基巯基乙酰胺作为金属-β-内酰胺酶 (MBL) 和铜绿假单胞菌毒力因子 LasB 的潜在多靶点抑制剂