日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeting tau in Alzheimer's Disease: rationale, approach and challenges

靶向治疗阿尔茨海默病中的tau蛋白:理论基础、方法和挑战

Aslanyan, Aram; Foiani, Martha S; Giovannucci, Tatiana A; McDade, Eric; Duff, Karen E; Mummery, Catherine J; Schöll, Michael; Wildsmith, Kristin R; Paterson, Ross W

Synapse vulnerability and resilience underlying Alzheimer's disease

突触脆弱性和恢复力是阿尔茨海默病的基础

Taddei, Raquel N; E Duff, Karen

Tau Oligomer-Containing Synapse Elimination by Microglia and Astrocytes in Alzheimer Disease

阿尔茨海默病中小胶质细胞和星形胶质细胞对含tau蛋白寡聚体的突触的清除

Taddei, Raquel N; Perbet, Romain; Mate de Gerando, Anastasie; Wiedmer, Anne E; Sanchez-Mico, Maria; Connors Stewart, Theresa; Gaona, Angelica; Melloni, Alexandra; Amaral, Ana C; Duff, Karen; Frosch, Matthew P; Gómez-Isla, Teresa

Effects of APOE4 allelic dosage on lipidomic signatures in the entorhinal cortex of aged mice

APOE4等位基因剂量对老年小鼠内嗅皮层脂质组学特征的影响

Miranda, André Miguel; Ashok, Archana; Chan, Robin Barry; Zhou, Bowen; Xu, Yimeng; McIntire, Laura Beth; Area-Gomez, Estela; Di Paolo, Gilbert; Duff, Karen E; Oliveira, Tiago Gil; Nuriel, Tal

In vivo rate-determining steps of tau seed accumulation in Alzheimer's disease

阿尔茨海默病中tau蛋白种子积累的体内限速步骤

Meisl, Georg; Hidari, Eric; Allinson, Kieren; Rittman, Timothy; DeVos, Sarah L; Sanchez, Justin S; Xu, Catherine K; Duff, Karen E; Johnson, Keith A; Rowe, James B; Hyman, Bradley T; Knowles, Tuomas P J; Klenerman, David

Chemogenetic attenuation of neuronal activity in the entorhinal cortex reduces Aβ and tau pathology in the hippocampus

化学遗传学方法减弱内嗅皮层神经元活动可减少海马体中的Aβ和tau蛋白病理。

Rodriguez, Gustavo A; Barrett, Geoffrey M; Duff, Karen E; Hussaini, S Abid

Atrophy associated with tau pathology precedes overt cell death in a mouse model of progressive tauopathy

在进行性tau蛋白病的鼠模型中,与tau蛋白病理相关的萎缩先于明显的细胞死亡。

Fung, Christine W; Guo, Jia; Fu, Hongjun; Figueroa, Helen Y; Konofagou, Elisa E; Duff, Karen E

Unilateral Focused Ultrasound-Induced Blood-Brain Barrier Opening Reduces Phosphorylated Tau from The rTg4510 Mouse Model

单侧聚焦超声诱导血脑屏障开放可降低rTg4510小鼠模型中的磷酸化tau蛋白水平

Karakatsani, Maria Eleni; Kugelman, Tara; Ji, Robin; Murillo, Maria; Wang, Shutao; Niimi, Yusuke; Small, Scott A; Duff, Karen E; Konofagou, Elisa E

Targeting the 26S Proteasome To Protect Against Proteotoxic Diseases

靶向26S蛋白酶体以预防蛋白毒性疾病

Myeku, Natura; Duff, Karen E

Selective vulnerability in neurodegenerative diseases

神经退行性疾病中的选择性脆弱性

Fu, Hongjun; Hardy, John; Duff, Karen E