日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Histone deacetylase inhibitor MS-275 restores social and synaptic function in a Shank3-deficient mouse model of autism.

组蛋白去乙酰化酶抑制剂 MS-275 可恢复 Shank3 缺陷型自闭症小鼠模型的社交和突触功能

期刊:Neuropsychopharmacology
影响因子:7.1
doi:10.1038/s41386-018-0073-1
Ma Kaijie, Qin Luye, Matas Emmanuel, Duffney Lara J, Liu Aiyi, Yan Zhen
免疫/内分泌
Mouse
乙酰化
发表日期：2018
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Brain region-specific disruption of Shank3 in mice reveals a dissociation for cortical and striatal circuits in autism-related behaviors

小鼠脑区特异性破坏Shank3基因揭示了自闭症相关行为中皮层和纹状体回路的分离

期刊:Translational Psychiatry
影响因子:6.2
doi:10.1038/s41398-018-0142-6
Bey, Alexandra L; Wang, Xiaoming; Yan, Haidun; Kim, Namsoo; Passman, Rebecca L; Yang, Yilin; Cao, Xinyu; Towers, Aaron J; Hulbert, Samuel W; Duffney, Lara J; Gaidis, Erin; Rodriguiz, Ramona M; Wetsel, William C; Yin, Henry H; Jiang, Yong-Hui
自闭症
神经科学
发表日期：2018
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Deficiency of Shank2 causes mania-like behavior that responds to mood stabilizers

Shank2基因缺陷会导致类似躁狂的行为，这种行为对情绪稳定剂有反应。

期刊:JCI Insight
影响因子:6.1
doi:10.1172/jci.insight.92052
Pappas, Andrea L; Bey, Alexandra L; Wang, Xiaoming; Rossi, Mark; Kim, Yong Ho; Yan, Haidun; Porkka, Fiona; Duffney, Lara J; Phillips, Samantha M; Cao, Xinyu; Ding, Jin-Dong; Rodriguiz, Ramona M; Yin, Henry H; Weinberg, Richard J; Ji, Ru-Rong; Wetsel, William C; Jiang, Yong-Hui
发表日期：2017
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Autism-like Deficits in Shank3-Deficient Mice Are Rescued by Targeting Actin Regulators

通过靶向肌动蛋白调节因子可以挽救Shank3缺陷小鼠的自闭症样缺陷

期刊:Cell Reports
影响因子:6.9
doi:10.1016/j.celrep.2015.04.064
Duffney, Lara J; Zhong, Ping; Wei, Jing; Matas, Emmanuel; Cheng, Jia; Qin, Luye; Ma, Kaijie; Dietz, David M; Kajiwara, Yuji; Buxbaum, Joseph D; Yan, Zhen
自闭症
神经科学
发表日期：2015
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Methylphenidate exerts dose-dependent effects on glutamate receptors and behaviors

哌甲酯对谷氨酸受体和行为具有剂量依赖性效应。

期刊:Biological Psychiatry
影响因子:9
doi:10.1016/j.biopsych.2014.04.003
Cheng, Jia; Xiong, Zhe; Duffney, Lara J; Wei, Jing; Liu, Aiyi; Liu, Sihang; Chen, Guo-Jun; Yan, Zhen
信号转导
发表日期：2014
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Impaired alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor trafficking and function by mutant huntingtin.

突变亨廷顿蛋白损害了α-氨基-3-羟基-5-甲基-4-异恶唑丙酸（AMPA）受体的运输和功能

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M111.236521
Mandal Madhuchhanda, Wei Jing, Zhong Ping, Cheng Jia, Duffney Lara J, Liu Wenhua, Yuen Eunice Y, Twelvetrees Alison E, Li Shihua, Li Xiao-Jiang, Kittler Josef T, Yan Zhen
免疫/内分泌
发表日期：2011
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