日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A cytokine network involving IL-36γ, IL-23, and IL-22 promotes antimicrobial defense and recovery from intestinal barrier damage

涉及 IL-36γ、IL-23 和 IL-22 的细胞因子网络促进抗菌防御和肠道屏障损伤的恢复

Vu L Ngo, Hirohito Abo, Estera Maxim, Akihito Harusato, Duke Geem, Oscar Medina-Contreras, Didier Merlin, Andrew T Gewirtz, Asma Nusrat, Timothy L Denning

Targeting intestinal inflammation with CD98 siRNA/PEI-loaded nanoparticles

利用载有 CD98 siRNA/PEI 的纳米粒子治疗肠道炎症

Hamed Laroui, Duke Geem, Bo Xiao, Emilie Viennois, Poonam Rakhya, Timothy Denning, Didier Merlin

Fab'-bearing siRNA TNFα-loaded nanoparticles targeted to colonic macrophages offer an effective therapy for experimental colitis

含有 Fab' 的 siRNA TNFα 纳米粒子靶向结肠巨噬细胞,为实验性结肠炎提供有效治疗方法

Hamed Laroui, Emilie Viennois, Bo Xiao, Brandon S B Canup, Duke Geem, Timothy L Denning, Didier Merlin

Specific microbiota-induced intestinal Th17 differentiation requires MHC class II but not GALT and mesenteric lymph nodes

特定微生物群诱导的肠道 Th17 分化需要 MHC II 类,但不需要 GALT 和肠系膜淋巴结

Duke Geem, Oscar Medina-Contreras, Michelle McBride, Rodney D Newberry, Pandelakis A Koni, Timothy L Denning

Functional specializations of intestinal dendritic cell and macrophage subsets that control Th17 and regulatory T cell responses are dependent on the T cell/APC ratio, source of mouse strain, and regional localization

控制 Th17 和调节性 T 细胞反应的肠道树突状细胞和巨噬细胞亚群的功能特化取决于 T 细胞/APC 比率、小鼠品系来源和区域定位

Timothy L Denning, Brian A Norris, Oscar Medina-Contreras, Santhakumar Manicassamy, Duke Geem, Rajat Madan, Christopher L Karp, Bali Pulendran