日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A genome-wide CRISPR screen identifies GRA38 as a key regulator of lipid homeostasis during Toxoplasma gondii adaptation to lipid-rich conditions

全基因组 CRISPR 筛选鉴定出 GRA38 是弓形虫适应富含脂质环境过程中脂质稳态的关键调控因子

Bitew, Mebratu A; Paredes-Santos, Tatiana C; Maru, Parag; Krishnamurthy, Shruthi; Wang, Yifan; Sangaré, Lamba O; Duley, Samuel; Yamaryo-Botté, Yoshiki; Botté, Cyrille Y; Saeij, Jeroen P J

A P5-ATPase, TgFLP12, diverging from plant chloroplast lipid transporters mediates apicoplast fatty export in Toxoplasma

一种与植物叶绿体脂质转运蛋白不同的P5-ATPase,TgFLP12,介导弓形虫顶质体中的脂肪输出。

Christophe-Sébastien Arnold,Anna-Maria Alazzi,Serena Shunmugam,Jan Janouškovec,Laurence Berry,Sarah Charital,Thierry Gautier,Samuel Duley,Delphine Jublot,Catherine Lemaire-Vieille,Marie-France Cesbron-Delauw,Pierre Cavailles,Jérôme Govin,Nicholas J Katris,Yoshiki Yamaryo-Botté,Cyrille Y Botté

A thymine-challenge test to prospectively evaluate dihydropyrimidine dehydrogenase activity for risk of severe 5-fluorouracil-induced gastrointestinal toxicity

胸腺嘧啶激发试验用于前瞻性地评估二氢嘧啶脱氢酶活性,以预测5-氟尿嘧啶引起的严重胃肠道毒性风险

Helsby, Nuala; Sharples, Katrina; Kim, Yu Jin; Porter, David; Burns, Kathryn; Jeong, Soo Hee; Benge, Sarah; Deva, Sanjeev; Lawrence, Ben; Jackson, Christopher; North, Richard; Strother, R Matthew; Duley, John; Findlay, Michael

Role of community pharmacy in the prevention of cardiovascular disease in minority ethnic groups in the UK including barriers and facilitators: protocol for a mixed methods systematic review

社区药房在英国少数族裔群体心血管疾病预防中的作用(包括障碍和促进因素):混合方法系统评价方案

Duley, Rumanveer Singh; Birdi, Gurkiran Kaur; Bush, Joseph; Connolly, Derek; Shoaib, Ahmad; Maidment, Ian

A genome-wide CRISPR screen identifies GRA38 as a key regulator of lipid homeostasis during Toxoplasma gondii adaptation to lipid-rich conditions.

全基因组 CRISPR 筛选发现 GRA38 是弓形虫适应富含脂质的环境过程中脂质稳态的关键调节因子

Bitew Mebratu A, Paredes-Santos Tatiana C, Maru Parag, Krishnamurthy Shruthi, Wang Yifan, Sangaré Lamba O, Duley Samuel, Yamaryo-Botté Yoshiki, Botte Cyrille, Saeij Jeroen P J

The acyl-CoA synthetase Tg ACS1 allows neutral lipid metabolism and extracellular motility in Toxoplasma gondii through relocation via its peroxisomal targeting sequence (PTS) under low nutrient conditions

在低营养条件下,酰基辅酶A合成酶Tg ACS1通过其过氧化物酶体靶向序列(PTS)的重定位,使弓形虫能够进行中性脂质代谢和胞外运动。

Sarah Charital #,Serena Shunmugam #,Sheena Dass,Anna Maria Alazzi,Christophe-Sébastien Arnold,Nicholas J Katris,Samuel Duley,Nyamekye A Quansah,Fabien Pierrel,Jérôme Govin,Yoshiki Yamaryo-Botté,Cyrille Y Botté

Toxoplasma acyl-CoA synthetase TgACS3 is crucial to channel host fatty acids in lipid droplets and for parasite propagation

弓形虫酰基辅酶A合成酶TgACS3对于将宿主脂肪酸输送到脂滴中以及寄生虫的繁殖至关重要。

Dass, Sheena; Shunmugam, Serena; Charital, Sarah; Duley, Samuel; Arnold, Christophe-Sébastien; Katris, Nicholas J; Cavaillès, Pierre; Cesbron-Delauw, Marie-France; Yamaryo-Botté, Yoshiki; Botté, Cyrille Y

Protocol for a multicentre randomised controlled trial examining the effects of temporarily pausing Bruton tyrosine kinase inhibitor therapy to coincide with SARS-CoV-2 vaccination and its impact on immune responses in patients with chronic lymphocytic leukaemia

一项多中心随机对照试验方案,旨在研究暂时暂停布鲁顿酪氨酸激酶抑制剂治疗以配合SARS-CoV-2疫苗接种的效果及其对慢性淋巴细胞白血病患者免疫反应的影响。

Barber, Vicki S; Peckham, Nicholas; Duley, Lelia; Francis, Anne; Abhishek, Abhishek; Moss, Paul; Cook, Jonathan A; Parry, Helen M

Poster (Clinical/Best Practice Implementation) ID 1985182: SCI-IEQCC Network and SCI-Ontario: Working together to develop a skin check video resource for pressure injury prevention in spinal cord injury

海报(临床/最佳实践实施)编号 1985182:SCI-IEQCC 网络和 SCI-Ontario:携手开发用于预防脊髓损伤患者压力性损伤的皮肤检查视频资源

Quatman-Yates, Catherine C; Myer, Gregory D; Ford, Kevin R; Hewett, Timothy E; Chase, Andrea D; Cordner, Sharol E; Duley, Jennifer M; Doupe, Marty; Giurleo, Charlie; Hong, Julianne W Y; Kras-Dupuis, Anna; Ventre, Anellina; Watson, Julie; Wolfe, Dalton L; Xia, Nancy

Skin care interventions in infants for preventing eczema and food allergy

婴儿皮肤护理干预措施,预防湿疹和食物过敏

Kelleher, Maeve M; Phillips, Rachel; Brown, Sara J; Cro, Suzie; Cornelius, Victoria; Carlsen, Karin C Lødrup; Skjerven, Håvard O; Rehbinder, Eva M; Lowe, Adrian J; Dissanayake, Eishika; Shimojo, Naoki; Yonezawa, Kaori; Ohya, Yukihiro; Yamamoto-Hanada, Kiwako; Morita, Kumiko; Axon, Emma; Cork, Michael; Cooke, Alison; Van Vogt, Eleanor; Schmitt, Jochen; Weidinger, Stephan; McClanahan, Danielle; Simpson, Eric; Duley, Lelia; Askie, Lisa M; Williams, Hywel C; Boyle, Robert J