日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Restoration of the Tumor Suppressor Function of Y220C-Mutant p53 by Rezatapopt, a Small-Molecule Reactivator.

Rezatapopt(一种小分子激活剂)可恢复 Y220C 突变 p53 的肿瘤抑制功能

Puzio-Kuter Anna M, Xu Lizhong, McBrayer Mary Kate, Dominique Romyr, Li Hongju H, Fahr Bruce J, Brown Alyssa M, Wiebesiek Amy E, Russo Brandon M, Mulligan Chris L, Yang Hong, Battaglia Josh, Robell Kimberly A, Thomas Dafydd H, Huang Kuo-Sen, Solovyov Alexander, Greenbaum Benjamin D, Oliner Jonathan D, Davis Thomas W, Dumble Melissa L, Johnson Melissa L, Xiong Shunbin, Yang Peirong, Lozano Guillermina, Fellous Marc M, Vu Binh T, Schram Alison M, Levine Arnold J, Poyurovsky Masha V

Discovery of Rezatapopt (PC14586), a First-in-Class, Small-Molecule Reactivator of p53 Y220C Mutant in Development

发现 Rezatapopt (PC14586),一种首创的小分子 p53 Y220C 突变体激活剂

Vu, Binh T; Dominique, Romyr; Fahr, Bruce J; Li, Hongju H; Fry, David C; Xu, Lizhong; Yang, Hong; Puzio-Kuter, Anna; Good, Andrew; Liu, Binbin; Huang, Kuo-Sen; Tanaka, Naoko; Davis, Thomas W; Dumble, Melissa L

Influences on Pregnant Women's and Health Care Professionals' Behaviour Regarding Maternal Vaccinations: A Qualitative Interview Study

影响孕妇和医护人员对孕妇疫苗接种行为的因素:一项定性访谈研究

Gauld, Natalie; Martin, Samuel; Sinclair, Owen; Petousis-Harris, Helen; Dumble, Felicity; Grant, Cameron C

Increasing Uptake of Maternal Pertussis Vaccinations through Funded Administration in Community Pharmacies

通过在社区药房提供资助来提高孕妇百日咳疫苗接种率

Howe, Anna S; Gauld, Natalie J; Cavadino, Alana Y; Petousis-Harris, Helen; Dumble, Felicity; Sinclair, Owen; Grant, Cameron C

Preclinical and Early Clinical Development of PTC596, a Novel Small-Molecule Tubulin-Binding Agent

新型小分子微管蛋白结合剂PTC596的临床前和早期临床开发

Jernigan, Finith; Branstrom, Arthur; Baird, John D; Cao, Liangxian; Dali, Mandar; Furia, Bansri; Kim, Min Jung; O'Keefe, Kylie; Kong, Ronald; Laskin, Oscar L; Colacino, Joseph M; Pykett, Mark; Mollin, Anna; Sheedy, Josephine; Dumble, Melissa; Moon, Young-Choon; Sheridan, Richard; Mühlethaler, Tobias; Spiegel, Robert J; Prota, Andrea E; Steinmetz, Michel O; Weetall, Marla

A Qualitative Study of Views and Experiences of Women and Health Care Professionals about Free Maternal Vaccinations Administered at Community Pharmacies

一项关于妇女和医护人员对社区药房提供的免费孕产妇疫苗接种的看法和经验的定性研究

Gauld, Natalie; Martin, Samuel; Sinclair, Owen; Petousis-Harris, Helen; Dumble, Felicity; Grant, Cameron C

Discovery and Optimization of Indolyl-Containing 4-Hydroxy-2-Pyridone Type II DNA Topoisomerase Inhibitors Active against Multidrug Resistant Gram-negative Bacteria

发现和优化含吲哚基的4-羟基-2-吡啶酮II型DNA拓扑异构酶抑制剂,该抑制剂对多重耐药革兰氏阴性菌具有活性

Gerasyuto, Aleksey I; Arnold, Michael A; Wang, Jiashi; Chen, Guangming; Zhang, Xiaoyan; Smith, Sean; Woll, Matthew G; Baird, John; Zhang, Nanjing; Almstead, Neil G; Narasimhan, Jana; Peddi, Srinivasa; Dumble, Melissa; Sheedy, Josephine; Weetall, Marla; Branstrom, Arthur A; Prasad, J V N; Karp, Gary M

Evaluating the Mechanism and Therapeutic Potential of PTC-028, a Novel Inhibitor of BMI-1 Function in Ovarian Cancer

评估新型BMI-1功能抑制剂PTC-028在卵巢癌中的作用机制及治疗潜力

Anindya Dey ,Xunhao Xiong ,Aleia Crim ,Shailendra Kumar Dhar Dwivedi ,Soumyajit Banerjee Mustafi ,Priyabrata Mukherjee ,Liangxian Cao ,Nadiya Sydorenko ,Ramil Baiazitov ,Young-Choon Moon ,Melissa Dumble ,Thomas Davis ,Resham Bhattacharya

Regression Analysis to Identify Factors Associated with Urinary Iodine Concentration at the Sub-National Level in India, Ghana, and Senegal

回归分析用于识别印度、加纳和塞内加尔次国家层面尿碘浓度的相关因素

Knowles, Jacky; Kupka, Roland; Dumble, Sam; Garrett, Greg S; Pandav, Chandrakant S; Yadav, Kapil; Touré, Ndeye Khady; Foriwa Amoaful, Esi; Gorstein, Jonathan

Regression Analysis to Identify Factors Associated with Household Salt Iodine Content at the Sub-National Level in Bangladesh, India, Ghana and Senegal

回归分析用于识别孟加拉国、印度、加纳和塞内加尔次国家层面家庭食盐碘含量的相关因素

Knowles, Jacky; Kupka, Roland; Dumble, Sam; Garrett, Greg S; Pandav, Chandrakant S; Yadav, Kapil; Nahar, Baitun; Touré, Ndeye Khady; Amoaful, Esi Foriwa; Gorstein, Jonathan