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Assessing Whether Providing Regular, Free HIV Self-Testing Kits Reduces the Time to HIV Diagnosis: An Internet-Based, Randomized Controlled Trial in Men Who Have Sex With Men

评估定期免费提供艾滋病毒自检试剂盒是否能缩短艾滋病毒诊断时间：一项针对男男性行为者的基于互联网的随机对照试验

期刊:Jaids-Journal of Acquired Immune Deficiency Syndromes

Dunn, David T; McCabe, Leanne; Ward, Denise; Phillips, Andrew N; Lampe, Fiona C; Burns, Fiona; Delpech, Valerie; Weatherburn, Peter; Witzel, T Charles; Pebody, Roger; Kirwan, Peter; Khawam, Jameel; Croxford, Sara; Brady, Michael; Fenton, Kevin A; Trevelion, Roy; Collaco-Moraes, Yolanda; McCormack, Sheena; Rodger, Alison J

Exploring different objectives in non-inferiority trials

探索非劣效性试验中的不同目标

期刊:Bmj-British Medical Journal

影响因子:42.7

doi:10.1136/bmj-2023-078000

Tweed, Conor D; Quartagno, Matteo; Clements, Michelle N; Turner, Rebecca M; Nunn, Andrew J; Dunn, David T; White, Ian R; Copas, Andrew J

发表日期：2024

文献求助收藏

Long-term efficacy and safety of a treatment strategy for HIV infection using protease inhibitor monotherapy: 8-year routine clinical care follow-up from a randomised, controlled, open-label pragmatic trial (PIVOT)

使用蛋白酶抑制剂单药治疗 HIV 感染的治疗策略的长期疗效和安全性：一项随机、对照、开放标签实用性试验 (PIVOT) 的 8 年常规临床护理随访

期刊:EClinicalMedicine

影响因子:10

doi:10.1016/j.eclinm.2024.102457

Paton, Nicholas I; Stöhr, Wolfgang; Arenas-Pinto, Alejandro; Clarke, Amanda; Williams, Ian; Johnson, Margaret; Orkin, Chloe; Chen, Fabian; Lee, Vincent; Winston, Alan; Gompels, Mark; Fox, Julie; Sanders, Karen; Dunn, David T

Needs & networks: understanding the role and impact of social networks on HIV (self-)testing among GBMSM and trans people in England and Wales

需求与网络：了解社交网络在英格兰和威尔士男男性行为者和跨性别者艾滋病毒（自我）检测中的作用和影响

期刊:BMC Public Health

影响因子:3.6

doi:10.1186/s12889-024-18487-w

Chu, Isaac Yen-Hao; Weatherburn, Peter; Wright, Talen; Samba, Phil; Nicholls, Emily Jay; McCabe, Leanne; Gafos, Mitzy; Dunn, David T; Trevelion, Roy; Burns, Fiona M; Rodger, Alison J; Witzel, T Charles

COVAC1 phase 2a expanded safety and immunogenicity study of a self-amplifying RNA vaccine against SARS-CoV-2

COVAC1 是一项针对 SARS-CoV-2 的自扩增 RNA 疫苗的 2a 期扩展安全性和免疫原性研究。

期刊:EClinicalMedicine

影响因子:10

doi:10.1016/j.eclinm.2022.101823

Szubert, Alex J; Pollock, Katrina M; Cheeseman, Hannah M; Alagaratnam, Jasmini; Bern, Henry; Bird, Olivia; Boffito, Marta; Byrne, Ruth; Cole, Tom; Cosgrove, Catherine A; Faust, Saul N; Fidler, Sarah; Galiza, Eva; Hassanin, Hana; Kalyan, Mohini; Libri, Vincenzo; McFarlane, Leon R; Milinkovic, Ana; O'Hara, Jessica; Owen, David R; Owens, Daniel; Pacurar, Mihaela; Rampling, Tommy; Skene, Simon; Winston, Alan; Woolley, James; Yim, Yee Ting N; Dunn, David T; McCormack, Sheena; Shattock, Robin J

Interpretation of active-control randomised trials: the case for a new analytical perspective involving averted events

对主动对照随机试验的解读：引入避免事件这一新的分析视角

期刊:BMC Medical Research Methodology

影响因子:3.4

doi:10.1186/s12874-023-01970-0

Dunn, David T; Stirrup, Oliver T; McCormack, Sheena; Glidden, David V

发表日期：2023

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Licenced doses of approved COVID-19 vaccines may not be optimal: A review of the early-phase, dose-finding trials

已获批准的新冠疫苗的许可剂量可能并非最佳：早期剂量探索试验回顾

期刊:

影响因子:

doi:10.1016/j.vaccine.2023.06.037

Dunn, David T; Gilson, Richard; McCormack, Sheena; McCoy, Laura E

Safety and immunogenicity of a self-amplifying RNA vaccine against COVID-19: COVAC1, a phase I, dose-ranging trial

针对新冠病毒的自扩增RNA疫苗的安全性和免疫原性：COVAC1，一项I期剂量探索试验

期刊:EClinicalMedicine

影响因子:10

doi:10.1016/j.eclinm.2021.101262

Pollock, Katrina M; Cheeseman, Hannah M; Szubert, Alexander J; Libri, Vincenzo; Boffito, Marta; Owen, David; Bern, Henry; O'Hara, Jessica; McFarlane, Leon R; Lemm, Nana-Marie; McKay, Paul F; Rampling, Tommy; Yim, Yee Ting N; Milinkovic, Ana; Kingsley, Cherry; Cole, Tom; Fagerbrink, Susanne; Aban, Marites; Tanaka, Maniola; Mehdipour, Savviz; Robbins, Alexander; Budd, William; Faust, Saul N; Hassanin, Hana; Cosgrove, Catherine A; Winston, Alan; Fidler, Sarah; Dunn, David T; McCormack, Sheena; Shattock, Robin J

Evidence for circulation of high-virulence HIV-1 subtype B variants in the United Kingdom

英国境内存在高致病性HIV-1 B亚型变异株传播的证据

Sample size estimation for the averted events ratio

避免事件比率的样本量估计

Assessing Whether Providing Regular, Free HIV Self-Testing Kits Reduces the Time to HIV Diagnosis: An Internet-Based, Randomized Controlled Trial in Men Who Have Sex With Men

评估定期免费提供艾滋病毒自检试剂盒是否能缩短艾滋病毒诊断时间：一项针对男男性行为者的基于互联网的随机对照试验

Exploring different objectives in non-inferiority trials

探索非劣效性试验中的不同目标

Long-term efficacy and safety of a treatment strategy for HIV infection using protease inhibitor monotherapy: 8-year routine clinical care follow-up from a randomised, controlled, open-label pragmatic trial (PIVOT)

使用蛋白酶抑制剂单药治疗 HIV 感染的治疗策略的长期疗效和安全性：一项随机、对照、开放标签实用性试验 (PIVOT) 的 8 年常规临床护理随访

Needs & networks: understanding the role and impact of social networks on HIV (self-)testing among GBMSM and trans people in England and Wales

需求与网络：了解社交网络在英格兰和威尔士男男性行为者和跨性别者艾滋病毒（自我）检测中的作用和影响

COVAC1 phase 2a expanded safety and immunogenicity study of a self-amplifying RNA vaccine against SARS-CoV-2

COVAC1 是一项针对 SARS-CoV-2 的自扩增 RNA 疫苗的 2a 期扩展安全性和免疫原性研究。

Interpretation of active-control randomised trials: the case for a new analytical perspective involving averted events

对主动对照随机试验的解读：引入避免事件这一新的分析视角

Licenced doses of approved COVID-19 vaccines may not be optimal: A review of the early-phase, dose-finding trials

已获批准的新冠疫苗的许可剂量可能并非最佳：早期剂量探索试验回顾

Safety and immunogenicity of a self-amplifying RNA vaccine against COVID-19: COVAC1, a phase I, dose-ranging trial

针对新冠病毒的自扩增RNA疫苗的安全性和免疫原性：COVAC1，一项I期剂量探索试验