Duo Chen相关文献与解析，生知库 | 链接生命科学的每一步

Systematic Engineering of Proteases in Saccharopolyspora Spinosa Reveals Synergistic Enhancement of Spinosad Biosynthesis via Substrate Flux Optimization

对棘孢糖多孢菌蛋白酶进行系统性改造，揭示了通过底物通量优化协同增强棘孢菌素生物合成的作用。

doi:10.1002/advs.202522638

Jin, Duo; Chen, Wangqiong; Yang, Danlu; Liu, Qing; Bai, Baolong; Dai, Zirui; Liu, Xirong; Zhu, Zirong; Rang, Jie; Xia, Liqiu

发表日期：2026

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Prenatal supplementation with the gut-derived tryptophan metabolite indole-3-propionic acid alleviates colitis susceptibility in maternal immune-activated offspring mice

产前补充肠道来源的色氨酸代谢产物吲哚-3-丙酸可减轻母体免疫激活子代小鼠的结肠炎易感性。

期刊:Journal of Advanced Research

影响因子:13

doi:10.1016/j.jare.2025.05.051

He, Ying; Ding, Chen; Zhang, Bo; Bao, Bingkun; Liu, Yantong; Yun, Duo; Chen, Xia; Guo, Rui; She, Yongbo; Liu, Zhigang

Fecal short-chain fatty acids and serum metabolites: the impact of COVID-19 infection on dialysis patients

粪便短链脂肪酸和血清代谢物：COVID-19 感染对透析患者的影响

期刊:Frontiers in Nutrition

影响因子:5.1

doi:10.3389/fnut.2026.1772671

Duan, Jiamin; Zhang, Jing; Li, Changlin; Li, Yuting; Yu, Duo; Chen, Yuwei; Yang, Qingli; Lin, Xiaomeng; Cai, Xudong

Enabling rapid and accurate grand discrimination of flue-cured tobacco: a near-infrared hyperspectral and machine learning approach

利用近红外高光谱和机器学习方法快速准确地鉴别烤烟：

期刊:Frontiers in Plant Science

影响因子:4.8

doi:10.3389/fpls.2026.1756218

Zou, Jiang; Gao, Hongbo; Wang, Duo; Chen, Yunquan; Deng, Shiyou; Shi, Nuo; Yang, Shengjie; Huang, Chunlin; Zi, Dingchun; Du, Yu; Bai, Yuxiang; Wang, Na; Wang, Ge; Liu, Zhengling; Zhang, Junhua; Zhou, Peng

发表日期：2026

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Independent and combined associations of blood selenium and physical activity with cognitive impairment in older adults: A dose-response analysis from NHANES

血液硒和体力活动与老年人认知障碍的独立及联合关联：来自NHANES的剂量反应分析

期刊:Journal of Nutrition Health & Aging

影响因子:4

doi:10.1016/j.jnha.2026.100851

Wu, Changzi; Wang, Wenpeng; Wang, Duo; Chen, Feier; Liu, Mengshuang; Wu, Zheng; Zhang, Bo; Chen, Tian

神经科学

发表日期：2026

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Newborn screening, genetic analysis, and long-term follow-up of 89 cases with short-chain acyl-CoA dehydrogenase deficiency (SCADD)

对 89 例短链酰基辅酶 A 脱氢酶缺乏症 (SCADD) 患者进行新生儿筛查、基因分析和长期随访

期刊:Molecular Genetics and Metabolism Reports

影响因子:1.9

doi:10.1016/j.ymgmr.2026.101292

Qian, GuLing; Liu, Chen; Xu, YanHua; Zhou, Duo; Chen, Chi; Wu, BenQing; Huang, XinWen

发表日期：2026

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Bimetallic Ca/Zn Nanoagonist Remould the Immunosuppressive Hepatocellular Carcinoma Microenvironment Following Incomplete Microwave Ablation via Pyroptosis and the STING Signaling Pathway

双金属钙/锌纳米激动剂通过细胞焦亡和STING信号通路重塑不完全微波消融后免疫抑制性肝细胞癌微环境

期刊:Advanced Science

影响因子:14.1

doi:10.1002/advs.202500670

Ling, Yuan; Liang, Xiayi; Yan, Kangning; Zeng, Guichun; Zhu, Xiaoqi; Jiang, Jinghang; Lu, Shaolong; Wang, Xiaobo; Zhou, Yuying; Li, Zhaoshen; Mai, Wei; Wang, Duo; Chen, Jie

A chromosome-level genome assembly of the Bullacta exarata (Cephalaspidea: Haminoeidae)

Bullacta exarata（头螺总科：Haminoeidae）的染色体水平基因组组装

期刊:Scientific Data

影响因子:6.9

doi:10.1038/s41597-025-05373-2

Zhao, Yongchao; Chi, Yong; Wu, Ailing; Wang, Yiwo; Li, Duo; Chen, Yusheng; Chen, Shuyin; Ji, Hongjiu; Li, Yangzhen

发表日期：2025

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GSK3Î± negatively regulates GSK3Î² by decreasing its protein levels and enzymatic activity in mouse embryonic stem cells.

在小鼠胚胎干细胞中，GSK3α通过降低其蛋白质水平和酶活性来负调控GSK3β

期刊:Stem Cell Reports

影响因子:5.1

doi:10.1016/j.stemcr.2025.102512

Wang Duo, Chen Xi, Feng Joshua, Jing Xueyuan A, Tang Jiaqi, Chadarevian Jean Paul, Park Haeyoung, Lee Matthew, Feng Fan, Zhang Chao, Ying Qi-Long

Disulfide-Bridged Ru Complex-Mediated Photo-Disulfidptosis for Colorectal Cancer Therapy

二硫键桥联钌络合物介导的光二硫键凋亡用于结直肠癌治疗

Systematic Engineering of Proteases in Saccharopolyspora Spinosa Reveals Synergistic Enhancement of Spinosad Biosynthesis via Substrate Flux Optimization

对棘孢糖多孢菌蛋白酶进行系统性改造，揭示了通过底物通量优化协同增强棘孢菌素生物合成的作用。

Prenatal supplementation with the gut-derived tryptophan metabolite indole-3-propionic acid alleviates colitis susceptibility in maternal immune-activated offspring mice

产前补充肠道来源的色氨酸代谢产物吲哚-3-丙酸可减轻母体免疫激活子代小鼠的结肠炎易感性。

Fecal short-chain fatty acids and serum metabolites: the impact of COVID-19 infection on dialysis patients

粪便短链脂肪酸和血清代谢物：COVID-19 感染对透析患者的影响

Enabling rapid and accurate grand discrimination of flue-cured tobacco: a near-infrared hyperspectral and machine learning approach

利用近红外高光谱和机器学习方法快速准确地鉴别烤烟：

Independent and combined associations of blood selenium and physical activity with cognitive impairment in older adults: A dose-response analysis from NHANES

血液硒和体力活动与老年人认知障碍的独立及联合关联：来自NHANES的剂量反应分析

Newborn screening, genetic analysis, and long-term follow-up of 89 cases with short-chain acyl-CoA dehydrogenase deficiency (SCADD)

对 89 例短链酰基辅酶 A 脱氢酶缺乏症 (SCADD) 患者进行新生儿筛查、基因分析和长期随访

Bimetallic Ca/Zn Nanoagonist Remould the Immunosuppressive Hepatocellular Carcinoma Microenvironment Following Incomplete Microwave Ablation via Pyroptosis and the STING Signaling Pathway

双金属钙/锌纳米激动剂通过细胞焦亡和STING信号通路重塑不完全微波消融后免疫抑制性肝细胞癌微环境

A chromosome-level genome assembly of the Bullacta exarata (Cephalaspidea: Haminoeidae)

Bullacta exarata（头螺总科：Haminoeidae）的染色体水平基因组组装

GSK3Î± negatively regulates GSK3Î² by decreasing its protein levels and enzymatic activity in mouse embryonic stem cells.

在小鼠胚胎干细胞中，GSK3α通过降低其蛋白质水平和酶活性来负调控GSK3β