Orally Bioavailable Cyclin A/B RxL Inhibitors: Optimization of a Novel Class of Macrocyclic Peptides That Target E2F-High and G1-S-Checkpoint-Compromised Cancers
口服生物利用度高的细胞周期蛋白A/B RxL抑制剂：针对E2F高表达和G1-S检查点受损癌症的新型大环肽的优化
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c02445
Shapiro, Justin A; Dupper, Nathan J; Fraga-Walton, Breena; Bockus, Andrew T; Leung, Siegfried S F; Yang, Kai; Bhatt, Chinmay; DeMart, Megan K; Baldomero, Miguel P; Hernandez, Luis; Fung, Gabriel; Metobo, Sammy; Xie, Steven; Lent, Bryan M; Spellmeyer, David C; Luna, Joshua; Hoang, Dalena; Chand, Manesh; Gritsenko, Yuliana; Gleason, Catherine E; Hamkins-Indik, Frances; Zheng, Jie; Odeh, Ranya; Nosrati, Meisam; He, Daphne; Bambal, Ramesh; Cremin, Peadar; Fang, Jinshu; Levin, Bernard; Wang, Evelyn W; Evangelista, Marie; Earp, David; Kreatsoulas, Constantine; Singh, Rajinder; Garcia, Pablo D; Aggen, James B
