Durell Stewart R相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

The concentric β-barrel hypothesis for amyloids: Models of soluble and transmembrane amyloid-β42 oligomers and channels composed of identical subunits and GM1 gangliosides

淀粉样蛋白的同心β桶假说：由相同亚基和GM1神经节苷脂组成的可溶性和跨膜淀粉样β42寡聚体和通道模型

doi:10.64898/2026.03.19.711324

Durell, Stewart R; Shafrir, Yinon; Guy, H Robert

发表日期：2026

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Conversion of Human Multidrug Transporter P-glycoprotein (ABCB1) from Drug Efflux to Uptake Pump: Evidence for a Switch Region Modulating the Direction of Substrate Transport

人多药转运蛋白P-糖蛋白（ABCB1）从药物外排泵向摄取泵的转化：调节底物转运方向的转换区证据

期刊:Journal of Molecular Biology

影响因子:4.5

doi:10.1016/j.jmb.2025.168979

Sajid, Andaleeb; Ranganathan, Nandhini; Guha, Rajan; Murakami, Megumi; Ahmed, Shafaq; Durell, Stewart R; Ambudkar, Suresh V

发表日期：2025

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Mutational analysis reveals the importance of residues of the access tunnel inhibitor site to human P-glycoprotein (ABCB1)-mediated transport

突变分析揭示了通道抑制位点残基对人P-糖蛋白（ABCB1）介导的转运的重要性

期刊:Protein Science

影响因子:5.2

doi:10.1002/pro.5155

Salazar, Paula B; Murakami, Megumi; Ranganathan, Nandhini; Durell, Stewart R; Ambudkar, Suresh V

发表日期：2024

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Second-site suppressor mutations reveal connection between the drug-binding pocket and nucleotide-binding domain 1 of human P-glycoprotein (ABCB1).

第二位点抑制突变揭示了人类 P-糖蛋白 (ABCB1) 的药物结合口袋与核苷酸结合域 1 之间的联系

期刊:Drug Resistance Updates

影响因子:21.7

doi:10.1016/j.drup.2023.101009

Murakami Megumi, Sajid Andaleeb, Lusvarghi Sabrina, Durell Stewart R, Abel Biebele, Vahedi Shahrooz, Golin John, Ambudkar Suresh V

免疫/内分泌

发表日期：2023

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Residues from Homologous Transmembrane Helices 4 and 10 Are Critical for P-Glycoprotein (ABCB1)-Mediated Drug Transport

同源跨膜螺旋4和10的残基对P-糖蛋白（ABCB1）介导的药物转运至关重要

影响因子:4.4

doi:10.3390/cancers15133459

Rahman, Hadiar; Ware, Mark J; Sajid, Andaleeb; Lusvarghi, Sabrina; Durell, Stewart R; Ambudkar, Suresh V

发表日期：2023

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Altering the Double-Stranded DNA Specificity of the bZIP Domain of Zta with Site-Directed Mutagenesis at N182

通过对 N182 位点进行定点诱变来改变 Zta 的 bZIP 结构域的双链 DNA 特异性

期刊:ACS Omega

影响因子:4.3

doi:10.1021/acsomega.1c04148

Ray, Sreejana; Tillo, Desiree; Assad, Nima; Ufot, Aniekanabasi; Porollo, Aleksey; Durell, Stewart R; Vinson, Charles

发表日期：2022

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A compendium of co-regulated mitoribosomal proteins in pan-cancer uncovers collateral defective events in tumor malignancy

泛癌中共调控线粒体核糖体蛋白的汇编揭示了肿瘤恶性转化中的伴随缺陷事件

期刊:iScience

影响因子:4.1

doi:10.1016/j.isci.2022.105244

Chang, Ching-Wen; Wei, Zhuang; Durell, Stewart R; Ma, Lichun; Forgues, Marshonna; Wang, Xin Wei

发表日期：2022

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The amyloid concentric β-barrel hypothesis: Models of synuclein oligomers, annular protofibrils, lipoproteins, and transmembrane channels

淀粉样蛋白同心β桶假说：突触核蛋白寡聚体、环状原纤维、脂蛋白和跨膜通道的模型

期刊:Proteins-Structure Function and Bioinformatics

影响因子:2.8

doi:10.1002/prot.26249

Durell, Stewart R; Guy, H Robert

发表日期：2022

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The amyloid concentric β-barrel hypothesis: Models of amyloid beta 42 oligomers and annular protofibrils

淀粉样蛋白同心β桶假说：淀粉样蛋白β42寡聚体和环状原纤维模型

期刊:Proteins-Structure Function and Bioinformatics

影响因子:2.8

doi:10.1002/prot.26301

Durell, Stewart R; Kayed, Rakez; Guy, H Robert

发表日期：2022

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REL Domain of NFATc2 Binding to Five Types of DNA Using Protein Binding Microarrays

利用蛋白质结合微阵列研究NFATc2的REL结构域与五种DNA的结合

期刊:ACS Omega

影响因子:4.3

doi:10.1021/acsomega.0c04069

Ray, Sreejana; Tillo, Desiree; Durell, Stewart R; Khund-Sayeed, Syed; Vinson, Charles

发表日期：2021

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