Discovery of small molecule modulators of the thin filament that alter the contractile profile in a hypertrophic cardiomyopathy engineered tissue model
在肥厚型心肌病工程组织模型中,发现了能够改变细丝收缩特性的小分子调节剂
期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2025.110938
Sommese, Ruth F; Levi, Samuel M; Brown, Janice; Polivkova, Jana; Byrnes, Laura J; Kue, Richard; Damilano, Federico; Hua, Wenyi; Boehm, Markus; Dushin, Elizabeth; Filipski, Kevin J; Kormos, Bethany L; Li, Qifang; Miller, Russell; Ogilvie, Kevin; Ridgway, Noelle; Smith, Aaron C; Stansfield, John C; Wang, Yang; Withka, Jane; Zhang, Hui; Griffith, David A; Ward, Jessica