日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Lytic IFNγ is stored in cytotoxic granules and coreleased with granzyme B to mediate cytotoxic T lymphocyte killing

裂解性IFNγ储存在细胞毒性颗粒中,并与颗粒酶B共同释放,介导细胞毒性T淋巴细胞杀伤作用。

Li, Xuemei; Schirra, Claudia; Wirkner, Marie-Louise; Tu, Szu-Min; Lin, Chin-Hsin; Hohmann, Meltem; Gu, Yuan; Santiago, Llipsy; Pardo, Julian; Arretxe, Iñaki; Alawar, Nadia; Chouaib, Abed Alrahman; Becherer, Ute; Lee, Po-Hsien; Hsu, Hao-Jen; Laschke, Matthias W; Baldari, Cosima T; Dustin, Michael L; Rettig, Jens; Krause, Elmar; Chang, Hsin-Fang

Autophagy-regulated mitochondrial inheritance controls early CD8(+) T cell fate commitment.

自噬调节的线粒体遗传控制早期 CD8(+) T 细胞命运决定。

Borsa Mariana, Lechuga-Vieco Ana Victoria, Kayvanjoo Amir H, Jenkins Edward, Yazicioglu Yavuz, Compeer Ewoud B, Richter Felix C, Rapp Simon, Mitchell Robert, Youdale Tom, Bui Hien, Kuuluvainen Emilia, Dustin Michael L, Sinclair Linda V, Katajisto Pekka, Simon Anna Katharina

T-Cell-Derived Exosomes From Multi Core Granules Exhibit Superior Caspase-3-Mediated Tumor-Suppressive Activity Compared to Those From Multivesicular Bodies

与多泡体来源的外泌体相比,多核颗粒来源的T细胞外泌体表现出更强的caspase-3介导的肿瘤抑制活性。

Alawar, Nadia; Schirra, Claudia; Rasuli, Ruth; Fecher-Trost, Claudia; Weins, Lisa; Meyer, Markus R; Flockerzi, Veit; Keller, A; Dustin, Michael L; Rettig, Jens; Becherer, Ute

Mixed-mobility supported lipid bilayers uncover the role of immobilized ICAM1 on T cell activation and immune synapse organization

混合迁移率支持的脂质双层揭示了固定化ICAM1在T细胞活化和免疫突触组织中的作用

Leithner, Alexander; Kvalvaag, Audun; Mitra, Tanmay; Valvo, Salvatore; Dada, Hannah; Compeer, Ewoud; Barton, Michael I; Eguiguren, Sofia Bustamante; Jenkins, Edward; Lagerholm, Christoffer; Dushek, Omer; Dustin, Michael L

isMap - immunological synapse map analysis program

isMap - 免疫突触图分析程序

Singleton, Amanda Holstad; Manet, Anthony; Valvo, Salvatore; Feenstra, Marike; Stenmark, Harald; Dustin, Michael L; Kvalvaag, Audun

Acetyl-CoA carboxylase 1 inhibition increases Treg metabolism and graft-versus-host disease treatment efficacy via mitochondrial fusion

乙酰辅酶A羧化酶1抑制剂通过线粒体融合增强Treg细胞代谢和移植物抗宿主病治疗效果。

McDonald-Hyman, Cameron; Aguilar, Ethan G; Compeer, Ewoud B; Zaiken, Michael C; Rhee, Stephanie Y; Mohamed, Fathima A; Larson, Jemma H; Loschi, Michael L; Lees, Christopher; Thangavelu, Govindarajan; Sleeth, Margaret L; Smith, Kyle D; Whangbo, Jennifer S; Ritz, Jerome; Sparwasser, Tim D; O'Connor, Roddy S; Crawford, Peter A; Rathmell, Jeffrey C; Kean, Leslie S; Zeiser, Robert; Hippen, Keli L; Dustin, Michael L; Blazar, Bruce R

Activation-induced thrombospondin-4 works with thrombospondin-1 to build cytotoxic supramolecular attack particles

活化诱导的血小板反应蛋白-4与血小板反应蛋白-1协同作用,构建细胞毒性超分子攻击颗粒。

Cassioli, Chiara; Capitani, Nagaja; Staton, Claire C; Schirra, Claudia; Finetti, Francesca; Onnis, Anna; Alawar, Nadia; Tu, Szu-Min; Lopresti, Ludovica; Tatangelo, Vanessa; Tangredi, Carmela; Valvo, Salvatore; Chang, Hsin-Fang; Miccoli, Annachiara; Compeer, Ewoud B; Nicholls, Jemma; Blazar, Bruce R; Marotta, Giuseppe; Wood, Matthew J A; Trentin, Livio; Patrussi, Laura; Dustin, Michael L; Becherer, Ute; Baldari, Cosima T

Molecular determinants for the endocytosis of the voltage-gated K(+) channel Kv1.3

电压门控K(+)通道Kv1.3内吞作用的分子决定因素

Estadella, Irene; Navarro-Pérez, María; Colomer-Molera, Magalí; Dustin, Michael L; Sorkin, Alexander; Capera, Jesusa; Felipe, Antonio

Low Levels of Mouse γδ T Cell Development Persist in the Presence of Null Mutants of the LAT Adaptor

即使存在 LAT 接头蛋白的缺失突变体,小鼠 γδ T 细胞的发育水平仍然很低。

Arbulo-Echevarria, Mikel M; Fernandez-Aguilar, Luis M; Kurz, Elke; Vico-Barranco, Inmaculada; Muñoz-Fernández, Raquel; Narbona-Sánchez, Isaac; Carrasco, Manuel; Malissen, Bernard; Dustin, Michael L; Aguado, Enrique

STAT3 phosphorylation in the rheumatoid arthritis immunological synapse

类风湿性关节炎免疫突触中的STAT3磷酸化

Kotzer, Hila Novak; Capera, Jesusa; Jainarayanan, Ashwin; Mayya, Viveka; Zanin-Zhorov, Alexandra; Valvo, Salvatore; Macdonald, Joanne; Taylor, Peter C; Dustin, Michael L