日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Potent Anti-SARS-CoV-2 Activity by the Natural Product Gallinamide A and Analogues via Inhibition of Cathepsin L

天然产物 Gallinamide A 及其类似物通过抑制组织蛋白酶 L 发挥强效抗 SARS-CoV-2 活性

Anneliese S Ashhurst, Arthur H Tang, Pavla Fajtová, Michael C Yoon, Anupriya Aggarwal, Max J Bedding, Alexander Stoye, Laura Beretta, Dustin Pwee, Aleksandra Drelich, Danielle Skinner, Linfeng Li, Thomas D Meek, James H McKerrow, Vivian Hook, Chien-Te Tseng, Mark Larance, Stuart Turville, William H

A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells

一类新型 TMPRSS2 抑制剂可有效阻断 SARS-CoV-2 和 MERS-CoV 病毒进入并保护人类上皮肺细胞

Matthew Mahoney, Vishnu C Damalanka, Michael A Tartell, Dong Hee Chung, André Luiz Lourenço, Dustin Pwee, Anne E Mayer Bridwell, Markus Hoffmann, Jorine Voss, Partha Karmakar, Nurit P Azouz, Andrea M Klingler, Paul W Rothlauf, Cassandra E Thompson, Melody Lee, Lidija Klampfer, Christina L Stallings,