日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

HER3-targeted protein chimera forms endosomolytic capsomeres and self-assembles into stealth nucleocapsids for systemic tumor homing of RNA interference in vivo

HER3 靶向蛋白嵌合体形成胞内溶酶体壳粒并自组装成隐形核衣壳,用于体内 RNA 干扰的系统性肿瘤归巢

Felix Alonso-Valenteen, Sayuri Pacheco, Dustin Srinivas, Altan Rentsendorj, David Chu, Jay Lubow, Jessica Sims, Tianxin Miao, Simoun Mikhael, Jae Youn Hwang, Ravinder Abrol, Lali K Medina Kauwe

Resistance to receptor-blocking therapies primes tumors as targets for HER3-homing nanobiologics

对受体阻断疗法的耐药性使肿瘤成为 HER3 归巢纳米生物制剂的靶点

Jessica D Sims, Jan Michael Taguiam, Felix Alonso-Valenteen, Janet Markman, Hasmik Agadjanian, David Chu, Jay Lubow, Ravinder Abrol, Dustin Srinivas, Anjali Jain, Bingchen Han, Ying Qu, Parisa Mirzadehgan, Jae-Youn Hwang, Altan Rentsendorj, Alice Chung, Jenny Lester, Beth Y Karlan, Harry B Gray, Zee

Bacterial expression, correct membrane targeting and functional folding of the HIV-1 membrane protein Vpu using a periplasmic signal peptide

利用周质信号肽对 HIV-1 膜蛋白 Vpu 进行细菌表达、正确膜靶向和功能性折叠

Arpan Deb, William A Johnson, Alexander P Kline, Boston J Scott, Lydia R Meador, Dustin Srinivas, Jose M Martin-Garcia, Katerina Dörner, Chad R Borges, Rajeev Misra, Brenda G Hogue, Petra Fromme, Tsafrir S Mor