日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Vm-MSI: a Vancomycin-Antimicrobial Peptide Conjugate Combating Resistant Bacteria and Broadening the Antimicrobial Spectrum

Vm-MSI：一种万古霉素-抗菌肽偶联物，可对抗耐药菌并拓宽抗菌谱

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202503023
Li, Shuangyu; Wang, Kang; Shi, Wenzhuang; Wang, Xu; Li, Duxin; Liu, Yanli; Zhang, Peng; Wang, Yipeng
多发性硬化症
发表日期：2026
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Discovery of SD-965 as a Potent, Selective, and Efficacious STAT3 PROTAC Degrader

发现 SD-965 是一种高效、选择性强且有效的 STAT3 PROTAC 降解剂

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c03767
Wu, Dimin; Zhou, Haibin; Bai, Longchuan; Acharyya, Ranjan Kumar; Metwally, Hoda; McEachern, Donna; Wang, Mi; Tošović, Jelena; Rej, Rohan Kalyan; Wang, Meilin; Wen, Bo; Sun, Duxin; Wang, Shaomeng
JAK/STAT
STAT3
发表日期：2026
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Investigation of Renal Tissue Deposition of the Calcineurin Inhibitors Voclosporin, Cyclosporine and Tacrolimus Using MALDI-MSI Imaging

利用MALDI-MSI成像技术研究钙调磷酸酶抑制剂沃克洛孢素、环孢素和他克莫司在肾脏组织中的沉积

期刊:Pharmaceutical Research
影响因子:4.3
doi:10.1007/s11095-025-03943-y
Zhou, Simon; Rajanayake, Krishani Kumari; He, Miao; Wen, Bo; Lkhagva, Ankhbayar; Yap, Ernie; Sun, Duxin; Cross, Jennifer; Engelke, Kory; Huizinga, Robert B
多发性硬化症
发表日期：2026
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SARS-CoV-2 B Epitope-Guided Neoantigen NanoVaccines Enhance Tumor-Specific CD4/CD8 T Cell Immunity through B Cell Antigen Presentation

SARS-CoV-2 B 表位引导的新抗原纳米疫苗通过 B 细胞抗原呈递增强肿瘤特异性 CD4/CD8 T 细胞免疫。

期刊:ACS Nano
影响因子:16
doi:10.1021/acsnano.4c15113
Li, Chengyi; Ke, Fang; Mao, Shuai; Montemayor, Zera; Traore, Mohamed Dit Mady; Balsa, Alejandra Duran; Djibo, Mahamadou; Karekar, Neha; Hu, Hongxiang; Wen, Hanning; Gao, Wei; Sun, Duxin
SARS-CoV-2
肿瘤
T细胞
肿瘤免疫
CD8
细胞生物学
CD4
免疫/内分泌
发表日期：2025
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The Fanconi anemia pathway repairs colibactin-induced DNA interstrand cross-links

范可尼贫血通路修复大肠杆菌素诱导的DNA链间交联

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-65606-1
Altshuller, Maria; He, Xu; MacKrell, Elliot J; Wernke, Kevin M; Airan, Yougant; Wong, Joel W H; Sellés-Baiget, Selene; Wang, Ting-Yu; Chou, Tsui-Fen; Duxin, Julien P; Balskus, Emily P; Herzon, Seth B; Semlow, Daniel R
信号转导
贫血
代谢
发表日期：2025
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Development of PVTX-405 as a potent and highly selective molecular glue degrader of IKZF2 for cancer immunotherapy

PVTX-405 的开发旨在将其作为一种高效且高选择性的 IKZF2 分子胶降解剂用于癌症免疫治疗。

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-025-58431-z
Zhixiang Chen # ，Harshil Dhruv # ，Xuqing Zhang # ，Rohan Kalyan Rej # ，Longchuan Bai # ，Donna McEachern ，Paul Kirchhoff ，Rakesh Nagilla ，Larry J Jolivette ，Cory T Rice ，Peter Orth ，Corey O Strickland ，E Scott Priestley ，Helai P Mohammad ，Meilin Wang ，Bo Wen ，Duxin Sun ，Zhihua Sui ，Shaomeng Wang
IKZF2
肿瘤
免疫/内分泌
肿瘤免疫
发表日期：2025
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CRAMP1-dependent histone H1 biogenesis is essential for topoisomerase II inhibitor tolerance

CRAMP1依赖的组蛋白H1生物合成对于拓扑异构酶II抑制剂耐受性至关重要

期刊:Molecular Cell
影响因子:14.5
doi:10.1016/j.molcel.2025.04.006
Andreas Ingham ,Ignacio Alonso de Vega ,Louise Morlot ,William Gittens ,Ivo A Hendriks ,Ellen S Kakulidis ,Raimundo Freire ,Norman E Davey ,Julien P Duxin ,Michael Lund Nielsen ,Niels Mailand
发表日期：2025
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Catalytic and noncatalytic functions of DNA polymerase κ in translesion DNA synthesis

DNA聚合酶κ在跨损伤DNA合成中的催化和非催化功能

期刊:Nature Structural & Molecular Biology
影响因子:12.5
doi:10.1038/s41594-024-01395-3
Selene Sellés-Baiget ,Sara M Ambjørn # ,Alberto Carli # ,Ivo A Hendriks # ,Irene Gallina ,Norman E Davey ,Bente Benedict ,Alessandra Zarantonello ,Sampath A Gadi ,Bob Meeusen ,Emil P T Hertz ,Laura Slappendel ,Daniel Semlow ,Shana Sturla ,Michael L Nielsen ,Jakob Nilsson ,Thomas C R Miller ,Julien P Duxin
发表日期：2025
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IDOL Deficiency Inhibits Cholesterol-Rich Diet-Induced Atherosclerosis in Rabbits

IDOL缺乏抑制高胆固醇饮食诱导的兔动脉粥样硬化

期刊:Arteriosclerosis Thrombosis and Vascular Biology
影响因子:7.4
doi:10.1161/ATVBAHA.125.322417
Koike, Tomonari; Koike, Yui; Niimi, Manabu; Guo, Yanhong; Yang, Dongshan; Song, Jun; Xu, Jie; Tang, Xiangming; Ren, Zhuoying; Kong, Xiangbo; Liu, Hongyu; Zhao, Xiangjie; Zhu, Tianqing; Li, Ruiting; Wen, Bo; Sun, Duxin; Rom, Oren; Han, Renzhi; Fan, Jianglin; Garcia-Barrio, Minerva T; Zhang, Jifeng; Chen, Y Eugene
IDO
Rabbit
心血管
代谢
动脉粥样硬化
发表日期：2025
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MD-4251: A First-in-Class Oral MDM2 Degrader Inducing Complete Tumor Regression with Single-Dose Administration

MD-4251：一种首创的口服MDM2降解剂，单次给药即可诱导肿瘤完全消退

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c00809
Acharyya, Ranjan Kumar; Huang, Liyue; Aguilar, Angelo; Hu, Biao; Bai, Longchuan; Metwally, Hoda; McEachern, Donna; Jiang, Wei; Wang, Yu; Li, Qiuxia; Wen, Bo; Sun, Duxin; Wang, Shaomeng
MDM2
肿瘤
肿瘤免疫
发表日期：2025
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