日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

MNK-driven eIF4E phosphorylation regulates the fibrogenic transformation of mesenchymal cells and chronic lung allograft dysfunction

MNK 驱动的 eIF4E 磷酸化调节间充质细胞的纤维化转化和慢性肺移植功能障碍

Natalie M Walker, Yuta Ibuki, A Patrick McLinden, Keizo Misumi, Dylan C Mitchell, Gabriel G Kleer, Alison M Lock, Ragini Vittal, Nahum Sonenberg, Amanda L Garner, Vibha N Lama

Highly specific intracellular ubiquitination of a small molecule

小分子的高度特异性细胞内泛素化

Weicheng Li, Enrique M Garcia-Rivera, Dylan C Mitchell, Joel M Chick, Micah Maetani, John M Knapp, Geoffrey M Matthews, Ryosuke Shirasaki, Ricardo de Matos Simoes, Vasanthi Viswanathan, John L Pulice, Matthew G Rees, Jennifer A Roth, Steven P Gygi, Constantine S Mitsiades, Cigall Kadoch, Stuart L Sc

A proteome-wide atlas of drug mechanism of action

药物作用机制的蛋白质组图谱

Dylan C Mitchell, Miljan Kuljanin, Jiaming Li, Jonathan G Van Vranken, Nathan Bulloch, Devin K Schweppe, Edward L Huttlin, Steven P Gygi

Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries

重新构想活性半胱氨酸的高通量分析,用于基于细胞的大型亲电试剂库筛选

Miljan Kuljanin, Dylan C Mitchell, Devin K Schweppe, Ajami S Gikandi, David P Nusinow, Nathan J Bulloch, Ekaterina V Vinogradova, David L Wilson, Eric T Kool, Joseph D Mancias, Benjamin F Cravatt, Steven P Gygi

Proteome-wide mapping of short-lived proteins in human cells

人类细胞中短寿命蛋白质的蛋白质组全图谱

Jiaming Li, Zhenying Cai, Laura Pontano Vaites, Ning Shen, Dylan C Mitchell, Edward L Huttlin, Joao A Paulo, Brian L Harry, Steven P Gygi

Assessing target engagement using proteome-wide solvent shift assays

使用蛋白质组范围溶剂转移分析评估靶标参与度

Jonathan G Van Vranken #, Jiaming Li #, Dylan C Mitchell, José Navarrete-Perea, Steven P Gygi

Cyclin-dependent kinase 4 inhibits the translational repressor 4E-BP1 to promote cap-dependent translation during mitosis-G1 transition

细胞周期蛋白依赖性激酶 4 抑制翻译阻遏物 4E-BP1,从而促进有丝分裂-G1 转换过程中的帽依赖性翻译

Dylan C Mitchell, Arya Menon, Amanda L Garner

Chemoproteomic Profiling Uncovers CDK4-Mediated Phosphorylation of the Translational Suppressor 4E-BP1

化学蛋白质组学分析揭示 CDK4 介导的翻译抑制因子 4E-BP1 磷酸化

Dylan C Mitchell, Arya Menon, Amanda L Garner