Saturation genome editing of 11 codons and exon 13 of BRCA2 coupled with chemotherapeutic drug response accurately determines pathogenicity of variants
BRCA2 的 11 个密码子和外显子 13 的饱和基因组编辑与化疗药物反应相结合可准确确定变异的致病性
期刊:PLoS Genetics
影响因子:
doi:10.1371/journal.pgen.1010940
Sounak Sahu, Teresa L Sullivan, Alexander Y Mitrophanov, Mélissa Galloux, Darryl Nousome, Eileen Southon, Dylan Caylor, Arun Prakash Mishra, Christine N Evans, Michelle E Clapp, Sandra Burkett, Tyler Malys, Raj Chari, Kajal Biswas, Shyam K Sharan
