日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Human-relevant mechanisms and risk factors for TAK-875-Induced liver injury identified via a gene pathway-based approach in Collaborative Cross mice

通过基于基因通路的方法，在协作交叉小鼠中鉴定出与人类相关的TAK-875诱导肝损伤机制和风险因素

期刊:Toxicology
影响因子:4.6
doi:10.1016/j.tox.2021.152902
Mosedale, Merrie; Cai, Yanwei; Eaddy, J Scott; Kirby, Patrick J; Wolenski, Francis S; Dragan, Yvonne; Valdar, William
Human
发表日期：2021
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Glutamate dehydrogenase as a biomarker for mitotoxicity; insights from furosemide hepatotoxicity in the mouse

谷氨酸脱氢酶作为线粒体毒性的生物标志物；来自呋塞米小鼠肝毒性的启示

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0240562
Church, Rachel J; Schomaker, Shelli J; Eaddy, J Scott; Boucher, Germaine G; Kreeger, John M; Aubrecht, Jiri; Watkins, Paul B
线粒体
毒理研究
发表日期：2020
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miR-122 Release in Exosomes Precedes Overt Tolvaptan-Induced Necrosis in a Primary Human Hepatocyte Micropatterned Coculture Model.

在原代人肝细胞微图案共培养模型中，外泌体中 miR-122 的释放先于托伐普坦诱导的明显坏死

期刊:Toxicological Sciences
影响因子:4.1
doi:10.1093/toxsci/kfx206
Mosedale Merrie, Eaddy J Scott, Trask O Joseph Jr, Holman Natalie S, Wolf Kristina K, LeCluyse Edward, Ware Brenton R, Khetani Salman R, Lu Jingtao, Brock William J, Roth Sharin E, Watkins Paul B
细胞生物学
Human
外泌体
发表日期：2018
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Editor's Highlight: Candidate Risk Factors and Mechanisms for Tolvaptan-Induced Liver Injury Are Identified Using a Collaborative Cross Approach

编辑推荐：采用跨学科合作方法识别托伐普坦诱导肝损伤的候选风险因素和机制

期刊:Toxicological Sciences
影响因子:4.1
doi:10.1093/toxsci/kfw269
Mosedale, Merrie; Kim, Yunjung; Brock, William J; Roth, Sharin E; Wiltshire, Tim; Eaddy, J Scott; Keele, Gregory R; Corty, Robert W; Xie, Yuying; Valdar, William; Watkins, Paul B
肝损伤
毒理研究
发表日期：2017
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A mouse diversity panel approach reveals the potential for clinical kidney injury due to DB289 not predicted by classical rodent models

利用小鼠多样性谱分析方法揭示了DB289可能导致临床肾损伤的可能性，而这种可能性是经典啮齿动物模型无法预测的。

期刊:Toxicological Sciences
影响因子:4.1
doi:10.1093/toxsci/kfs238
Harrill, Alison H; Desmet, Kristina D; Wolf, Kristina K; Bridges, Arlene S; Eaddy, J Scott; Kurtz, C Lisa; Hall, J Ed; Paine, Mary F; Tidwell, Richard R; Watkins, Paul B
毒理研究
肾损伤
发表日期：2012
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