日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Membrane Perturbations and Assay Interferences by Ivermectin Explain Its In Vitro SARS-CoV-2 Antiviral Activities and Lack of Translatability

伊维菌素引起的膜扰动和检测干扰解释了其体外抗SARS-CoV-2病毒活性及其缺乏转化性的原因

Eastman, Richard T; Rusinova, Radda; Herold, Karl F; Huang, Xi-Ping; Voss, Ty; White, Alex D; Hemmings, Hugh C Jr; Andersen, Olaf S; Dahlin, Jayme L

Establishment of human post-vaccination SARS-CoV-2 standard reference sera.

建立人类接种SARS-CoV-2疫苗后的标准参考血清

Xiang Jinhua, Katz Louis, Winokur Patricia L, Chaudhary Ashok, Digmann Barbara, Bradford Rebecca, Rashid Sujatha, Ghosh Sudakshina, Robertson Angela, Menetski Joseph, Xu Miao, Gao Peng, Chen Catherine Z, Lee Taylor, Poelaert Brittany, Eastman Richard T, Hall Matthew D, Stapleton Jack T

A Plasmodium falciparum RING Finger E3 Ubiquitin Ligase Modifies the Roles of PfMDR1 and PfCRT in Parasite Drug Responses

恶性疟原虫RING指E3泛素连接酶改变PfMDR1和PfCRT在寄生虫药物反应中的作用

Singh, Brajesh K; Zhang, Cui; Wu, Jian; Peng, Yu-Chih; He, Xiao; Tumas, Keyla C; Sá, Juliana M; Lane, Kristin D; Eastman, Richard T; Narum, David L; Wellems, Thomas E; Su, Xin-Zhuan

Quantitative Bioactivity Signatures of Dietary Supplements and Natural Products

膳食补充剂和天然产物的定量生物活性特征

Yasgar, Adam; Bougie, Danielle; Eastman, Richard T; Huang, Ruili; Itkin, Misha; Kouznetsova, Jennifer; Lynch, Caitlin; McKnight, Crystal; Miller, Mitch; Ngan, Deborah K; Peryea, Tyler; Shah, Pranav; Shinn, Paul; Xia, Menghang; Xu, Xin; Zakharov, Alexey V; Simeonov, Anton

A platform of assays for the discovery of anti-Zika small-molecules with activity in a 3D-bioprinted outer-blood-retina model

用于发现对3D生物打印外血视网膜模型具有活性的抗寨卡小分子的检测平台

Dorjsuren, Dorjbal; Eastman, Richard T; Song, Min Jae; Yasgar, Adam; Chen, Yuchi; Bharti, Kapil; Zakharov, Alexey V; Jadhav, Ajit; Ferrer, Marc; Shi, Pei-Yong; Simeonov, Anton

Small Molecule Antiviral Compound Collection (SMACC): a database to support the discovery of broad-spectrum antiviral drug molecules

小分子抗病毒化合物库(SMACC):一个支持发现广谱抗病毒药物分子的数据库

Martin, Holli-Joi; Melo-Filho, Cleber C; Korn, Daniel; Eastman, Richard T; Rai, Ganesha; Simeonov, Anton; Zakharov, Alexey V; Muratov, Eugene; Tropsha, Alexander

Chemoprotective antimalarials identified through quantitative high-throughput screening of Plasmodium blood and liver stage parasites

通过对疟原虫血液期和肝脏期寄生虫进行定量高通量筛选,鉴定出具有化学保护作用的抗疟药

Dorjsuren, Dorjbal; Eastman, Richard T; Wicht, Kathryn J; Jansen, Daniel; Talley, Daniel C; Sigmon, Benjamin A; Zakharov, Alexey V; Roncal, Norma; Girvin, Andrew T; Antonova-Koch, Yevgeniya; Will, Paul M; Shah, Pranav; Sun, Hongmao; Klumpp-Thomas, Carleen; Mok, Sachel; Yeo, Tomas; Meister, Stephan; Marugan, Juan Jose; Ross, Leila S; Xu, Xin; Maloney, David J; Jadhav, Ajit; Mott, Bryan T; Sciotti, Richard J; Winzeler, Elizabeth A; Waters, Norman C; Campbell, Robert F; Huang, Wenwei; Simeonov, Anton; Fidock, David A

Application of niclosamide and analogs as small molecule inhibitors of Zika virus and SARS-CoV-2 infection

尼克酰胺及其类似物作为寨卡病毒和SARS-CoV-2感染的小分子抑制剂的应用

Shamim, Khalida; Xu, Miao; Hu, Xin; Lee, Emily M; Lu, Xiao; Huang, Ruili; Shah, Pranav; Xu, Xin; Chen, Catherine Z; Shen, Min; Guo, Hui; Chen, Lu; Itkin, Zina; Eastman, Richard T; Shinn, Paul; Klumpp-Thomas, Carleen; Michael, Sam; Simeonov, Anton; Lo, Donald C; Ming, Guo-Li; Song, Hongjun; Tang, Hengli; Zheng, Wei; Huang, Wenwei

Remdesivir: A Review of Its Discovery and Development Leading to Emergency Use Authorization for Treatment of COVID-19

瑞德西韦:回顾其发现和研发历程,直至获得紧急使用授权用于治疗新冠肺炎

Eastman, Richard T; Roth, Jacob S; Brimacombe, Kyle R; Simeonov, Anton; Shen, Min; Patnaik, Samarjit; Hall, Matthew D

Correction to Remdesivir: A Review of Its Discovery and Development Leading to Human Clinical Trials for Treatment of COVID-19

关于瑞德西韦的更正:回顾其发现和研发历程,直至开展治疗新冠肺炎的人体临床试验

Eastman, Richard T; Roth, Jacob S; Brimacombe, Kyle R; Simeonov, Anton; Shen, Min; Patnaik, Samarjit; Hall, Matthew D