Antibodies toward Na+,HCO3--cotransporter NBCn1/SLC4A7 block net acid extrusion and cause pH-dependent growth inhibition and apoptosis in breast cancer
针对 Na+、HCO3- 协同转运蛋白 NBCn1/SLC4A7 的抗体可阻断净酸挤出并导致乳腺癌中 pH 依赖性生长抑制和细胞凋亡
期刊:British Journal of Cancer
影响因子:6.4
doi:10.1038/s41416-024-02591-0
Trine V Axelsen, Claus Olesen, Danish Khan, Ali Mohammadi, Elena V Bouzinova, Christine J F Nielsen, Marco Mele, Katrine R Hauerslev, Helene L Pedersen, Eva Balling, Pernille Vahl, Trine Tramm, Peer M Christiansen, Ebbe Boedtkjer
信号转导
细胞生物学
肿瘤
乳腺癌
其它细胞
Apoptosis