日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Safety, tolerability, and immunogenicity of INO-4500, a synthetic DNA-based vaccine against Lassa virus, in a phase 1b clinical trial in healthy Ghanaian adults

在加纳健康成年人中开展的 1b 期临床试验中,研究人员评估了 INO-4500(一种合成 DNA 疫苗,用于预防拉沙病毒)的安全性、耐受性和免疫原性。

Koram, Kwadwo Ansah; Walker, Kathleen A; Orizu, Bonaventure; Marrero, Idania; Boyer, Jean; Yang, ShuPing; Broderick, Kate E; Kusi, Kwadwo Asamoah; Kyei-Baafour, Eric; Ofori, Ebenezer Addo; Pobee, Abigail; Adu-Amankwah, Susan; Amoakoh-Coleman, Mary; Amoakoh, Hannah Brown; Abuaku, Benjamin; Badji, Edem; Ntiri, Michael; Quaye, Lydia; Morrow, Matthew P; Sylvester, Albert J; Reuschel, Emma L; Gillespie, Elisabeth; Liebowitz, David; Humeau, Laurent M

A randomized first-in-human phase I trial of differentially adjuvanted Pfs48/45 malaria vaccines in Burkinabé adults

一项在布基纳法索成年人中开展的随机首次人体I期临床试验,研究不同佐剂的Pfs48/45疟疾疫苗的疗效

Tiono, Alfred B; Plieskatt, Jordan L; Ouedraogo, Alphonse; Soulama, Ben Idriss; Miura, Kazutoyo; Bougouma, Edith C; Naghizadeh, Mohammad; Barry, Aissata; Yaro, Jean Baptist B; Ezinmegnon, Sem; Henry, Noelie; Ofori, Ebenezer Addo; Adu, Bright; Singh, Susheel K; Konkobo, Augustin; Lövgren Bengtsson, Karin; Diarra, Amidou; Carnrot, Cecilia; Reimer, Jenny M; Ouedraogo, Amidou; Tienta, Moussa; Long, Carole A; Ouedraogo, Issa N; Sagara, Issaka; Sirima, Sodiomon B; Theisen, Michael

ProC6C, a novel multi-stage malaria vaccine, elicits functional antibodies against the minor and central repeats of the Circumsporozoite Protein in human adults

ProC6C是一种新型多阶段疟疾疫苗,可在成人体内诱导产生针对环子孢子蛋白次要重复序列和中心重复序列的功能性抗体。

Plieskatt, Jordan; Ofori, Ebenezer Addo; Naghizadeh, Mohammad; Miura, Kazutoyo; Flores-Garcia, Yevel; Borbye-Lorenzen, Nis; Tiono, Alfred B; Skogstrand, Kristin; Sagara, Issaka; Zavala, Fidel; Theisen, Michael

Human blood neutrophils generate ROS through FcγR-signaling to mediate protection against febrile P. falciparum malaria

人类血液中性粒细胞通过 FcγR 信号产生 ROS,从而介导对发热性恶性疟原虫疟疾的保护作用

Ebenezer Addo Ofori #, Asier Garcia-Senosiain #, Mohammad Naghizadeh, Ikhlaq Hussain Kana, Morten Hanefeld Dziegiel, Bright Adu, Subhash Singh, Michael Theisen

Macrophage susceptibility to infection by Ghanaian Mycobacterium tuberculosis complex lineages 4 and 5 varies with self-reported ethnicity

巨噬细胞对加纳结核分枝杆菌复合群4系和5系的感染易感性随自我报告的种族而变化

Osei-Wusu, Stephen; Tetteh, John K A; Musah, Abdul Basit; Ntiamoah, Desmond Opoku; Arthur, Nelly; Adjei, Abraham; Arbues, Ainhoa; Ofori, Ebenezer Addo; Mensah, Kwadwo Akyea; Galevo, Sutaya Elsie Afua; Frempong, Abena Frema; Asare, Prince; Asante-Poku, Adwoa; Otchere, Isaac Darko; Kusi, Kwadwo Asamoah; Lenz, Tobias L; Gagneux, Sebastien; Portevin, Damien; Yeboah-Manu, Dorothy

Asymptomatic Malaria Infection Is Maintained by a Balanced Pro- and Anti-inflammatory Response

无症状疟疾感染由平衡的促炎和抗炎反应维持

Augustina Frimpong, Jones Amponsah, Abigail Sena Adjokatseh, Dorothy Agyemang, Lutterodt Bentum-Ennin, Ebenezer Addo Ofori, Eric Kyei-Baafour, Kwadwo Akyea-Mensah, Bright Adu, Gloria Ivy Mensah, Linda Eva Amoah, Kwadwo Asamoah Kusi

Prevalence of sickle cell disorders and malaria infection in children aged 1-12 years in the Volta Region, Ghana: a community-based study

加纳沃尔特地区 1-12 岁儿童镰状细胞病和疟疾感染的患病率:一项基于社区的研究

Mavis Oppong, Helena Lamptey, Eric Kyei-Baafour, Belinda Aculley, Ebenezer Addo Ofori, Bernard Tornyigah, Margaret Kweku, Michael F Ofori