日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genomic and Molecular Associations with Preoperative Immune Checkpoint Inhibition in Patients with Stage III Clear Cell Renal Cell Carcinoma

III期透明细胞肾细胞癌患者术前免疫检查点抑制的基因组和分子关联

Chou, Wesley H; Lawrence, Lucy; Neham, Emma; Akilesh, Shreeram; Moran, Amy E; Corless, Christopher L; Langmesser, Lisa; Cengiz, Beyza; Eckenstein, Kazumi; Liu, Jen-Jane; Isharwal, Sudhir; Amling, Christopher L; Strother, Marshall C; Chakiryan, Nicholas H; Thomas, George V

Sphingosine simultaneously inhibits nuclear import and activates PP2A by binding importins and PPP2R1A

鞘氨醇通过与输入蛋白和PPP2R1A结合,同时抑制核输入并激活PP2A。

Vaishali Jayashankar # ,Peter Kubiniok # ,Alison N McCracken # ,Rebeca G Gentry ,Kazumi H Eckenstein ,Lorenzo Sernissi ,Vito Vece ,Jean-Baptiste Garsi ,Sarah Y Valles ,Sunhee Jung ,Natalie C Hoffman ,Arielle S Perrochon ,Elizabeth M Selwan ,Brendan T Finicle ,Mary Pitman ,DaWei Lin ,Éric Bonneil ,Ruijuan Xu ,Cungui Mao ,Peter Kaiser ,David A Fruman ,David Mobley ,Cholsoon Jang ,Stephen Hanessian ,Pierre Thibault ,Aimee L Edinger

Mitochondrial Translation Inhibition Uncovers a Critical Metabolic-Epigenetic Interface in Renal Cell Carcinoma

线粒体翻译抑制揭示肾细胞癌中的关键代谢-表观遗传界面

Kazumi Eckenstein ,Beyza Cengiz ,Matthew E K Chang ,Jessie May Cartier ,Mark R Flory ,George V Thomas

Genomic and molecular associations with preoperative immune checkpoint inhibition in patients with stage III clear cell renal cell carcinoma

III期透明细胞肾细胞癌患者术前免疫检查点抑制的基因组和分子关联

Chou, Wesley H; Lawrence, Lucy; Neham, Emma; Akilesh, Shreeram; Moran, Amy E; Corless, Christopher L; Langmesser, Lisa; Cengiz, Beyza; Eckenstein, Kazumi; Liu, Jen-Jane; Isharwal, Sudhir; Amling, Christopher L; Strother, Marshall C; Chakiryan, Nicholas H; Thomas, George V

Mitochondrial Translation Inhibition Uncovers a Critical Metabolic-Epigenetic Interface in Renal Cell Carcinoma.

线粒体翻译抑制揭示肾细胞癌中的关键代谢-表观遗传界面

Eckenstein Kazumi, Cengiz Beyza, Chang Matthew E K, Cartier Jessie May, Flory Mark R, Thomas George V

Phase 1b/2 study of orally administered pexidartinib in combination with radiation therapy and temozolomide in patients with newly diagnosed glioblastoma

一项针对新诊断胶质母细胞瘤患者的口服pexidartinib联合放射疗法和替莫唑胺的1b/2期研究

Mendez, Joe S; Cohen, Adam L; Eckenstein, Midori; Jensen, Randy L; Burt, Lindsay M; Salzman, Karen L; Chamberlain, Marc; Hsu, Henry H; Hutchinson, Marguerite; Iwamoto, Fabio; Ligon, Keith L; Mrugala, Maciej M; Pelayo, Michael; Plotkin, Scott R; Puduvalli, Vinay K; Raizer, Jeffrey; Reardon, David A; Sterba, Michael; Walbert, Tobias; West, Brian L; Wong, Eric T; Zhang, Chao; Colman, Howard

Simultaneous inhibition of endocytic recycling and lysosomal fusion sensitizes cells and tissues to oligonucleotide therapeutics

同时抑制内吞循环和溶酶体融合使细胞和组织对寡核苷酸疗法敏感

Brendan T Finicle, Kazumi H Eckenstein, Alexey S Revenko, Brooke A Anderson, W Brad Wan, Alison N McCracken, Daniel Gil, David A Fruman, Stephen Hanessian, Punit P Seth, Aimee L Edinger

Drug-like sphingolipid SH-BC-893 opposes ceramide-induced mitochondrial fission and corrects diet-induced obesity

类药物鞘脂 SH-BC-893 可抵抗神经酰胺诱导的线粒体裂变并纠正饮食引起的肥胖

Vaishali Jayashankar, Elizabeth Selwan, Sarah E Hancock, Amandine Verlande, Maggie O Goodson, Kazumi H Eckenstein, Giedre Milinkeviciute, Brianna M Hoover, Bin Chen, Angela G Fleischman, Karina S Cramer, Stephen Hanessian, Selma Masri, Nigel Turner, Aimee L Edinger

Primary and secondary motoneurons use different calcium channel types to control escape and swimming behaviors in zebrafish

初级和次级运动神经元使用不同类型的钙通道来控制斑马鱼的逃逸和游泳行为

Hua Wen, Kazumi Eckenstein, Vivien Weihrauch, Christian Stigloher, Paul Brehm

Threonyl-tRNA synthetase overexpression correlates with angiogenic markers and progression of human ovarian cancer

苏氨酰-tRNA 合成酶过度表达与血管生成标志物和人类卵巢癌进展相关

Theresa L Wellman, Midori Eckenstein, Cheung Wong, Mercedes Rincon, Takamaru Ashikaga, Sharon L Mount, Christopher S Francklyn, Karen M Lounsbury