日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Development of a targeted BioPROTAC degrader selective for misfolded SOD1

开发一种针对错误折叠的SOD1的靶向BioPROTAC降解剂

Chisholm, Christen G; Bartlett, Rachael; Brown, Mikayla L; Proctor, Emma-Jayne; Farrawell, Natalie E; Gorman, Jody; Delerue, Fabien; Ittner, Lars M; Vine-Perrow, Kara L; Ecroyd, Heath; Cashman, Neil R; Saunders, Darren N; McAlary, Luke; Lum, Jeremy S; Yerbury, Justin J

A polytherapy approach demonstrates therapeutic efficacy for the treatment of SOD1 associated amyotrophic lateral sclerosis.

多药联合疗法对治疗 SOD1 相关肌萎缩侧索硬化症具有疗效

Lum Jeremy S, Brown Mikayla L, Farrawell Natalie E, Bartlett Rachael, Chisholm Christen G, Gorman Jody, Dosseto Anthony, Dux Florian, McInnes Lachlan E, Ecroyd Heath, McAlary Luke, Crouch Peter J, Donnelly Paul S, Yerbury Justin J

Competing chaperone pathways in α-synuclein disaggregation and aggregation dynamics.

α-突触核蛋白解聚和聚集动力学中的竞争性分子伴侣通路。

Auld Nicola K, McMahon Shannon, Marzano Nicholas R, van Oijen Antoine M, Ecroyd Heath

Single-molecule observations of human small heat shock proteins in complex with aggregation-prone client proteins.

利用单分子方法观察人类小热休克蛋白与易聚集底物蛋白的复合物

Rice Lauren, Marzano Nicholas, Cox Dezerae, Skewes Bailey, van Oijen Antoine M, Ecroyd Heath

Stress biology: Complexity and multifariousness in health and disease

压力生物学:健康和疾病的复杂性和多样性

Matthias P Mayer, Laura Blair, Gregory L Blatch, Thiago J Borges, Ahmed Chadli, Gabriela Chiosis, Aurélie de Thonel, Albena Dinkova-Kostova, Heath Ecroyd, Adrienne L Edkins, Takanori Eguchi, Monika Fleshner, Kevin P Foley, Sotirios Fragkostefanakis, Jason Gestwicki, Pierre Goloubinoff, Jennifer A He

The beauty and complexity of the small heat shock proteins: a report on the proceedings of the fourth workshop on small heat shock proteins

小分子热休克蛋白之美与复杂性:第四届小分子热休克蛋白研讨会论文集报告

Ecroyd, Heath; Bartelt-Kirbach, Britta; Ben-Zvi, Anat; Bonavita, Raffaella; Bushman, Yevheniia; Casarotto, Elena; Cecconi, Ciro; Lau, Wilson Chun Yu; Hibshman, Jonathan D; Joosten, Joep; Kimonis, Virginia; Klevit, Rachel; Liberek, Krzysztof; McMenimen, Kathryn A; Miwa, Tsukumi; Mogk, Axel; Montepietra, Daniele; Peters, Carsten; Rocchetti, Maria Teresa; Saman, Dominik; Sisto, Angela; Secco, Valentina; Strauch, Annika; Taguchi, Hideki; Tanguay, Morgan; Tedesco, Barbara; Toth, Melinda E; Wang, Zihao; Benesch, Justin L P; Carra, Serena

Real-time single-molecule observation of chaperone-assisted protein folding

实时单分子观测分子伴侣辅助的蛋白质折叠

Marzano, Nicholas R; Paudel, Bishnu P; van Oijen, Antoine M; Ecroyd, Heath

Exploiting flow cytometry for the unbiased quantification of protein inclusions in Caenorhabditis elegans

利用流式细胞术对秀丽隐杆线虫中的蛋白质内含物进行无偏定量分析

Kristian Claesson, Yee Lian Chew, Heath Ecroyd

Regional Differences in Heat Shock Protein 25 Expression in Brain and Spinal Cord Astrocytes of Wild-Type and SOD1 G93A Mice

野生型和SOD1 G93A小鼠脑和脊髓星形胶质细胞中热休克蛋白25表达的区域差异

Rebecca San Gil ,Benjamin E Clarke ,Heath Ecroyd ,Bernadett Kalmar ,Linda Greensmith

Proteostasis in the Male and Female Germline: A New Outlook on the Maintenance of Reproductive Health

男性和女性生殖细胞系中的蛋白质稳态:维持生殖健康的新视角

Cafe, Shenae L; Nixon, Brett; Ecroyd, Heath; Martin, Jacinta H; Skerrett-Byrne, David A; Bromfield, Elizabeth G