日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Distinguishing Pseudotransduction and True Transduction Enables Characterization and Bioengineering of Extracellular Vesicle-Adeno-Associated Virus Vectors

区分假性转导和真性转导有助于表征和生物工程改造细胞外囊泡腺相关病毒载体

Boucher, Jonathan D; Stranford, Devin M; Edelstein, Hailey I; Tullman-Ercek, Danielle; Kamat, Neha P; Leonard, Joshua N

GCAD: A Computational Framework for Mammalian Genetic Program Computer-Aided Design

GCAD:哺乳动物遗传程序计算机辅助设计的计算框架

Dreyer, Kathleen S; Nguyen, Anh V; Bora, Gauri G; Redus, Lauren E; Edelstein, Hailey I; Garcia, Jocelyn J; Anastasia, Eleftheria; Dray, Kate E; Leonard, Joshua N; Mangan, Niall M

Conversion of natural cytokine receptors into orthogonal synthetic biosensors.

将天然细胞因子受体转化为正交合成生物传感器

Edelstein Hailey I, Cosio Amparo, Ezekiel Max L, Corcoran William K, Morris Aaron H, Leonard Joshua N

Engineered Feedback Employing Natural Hypoxia-Responsive Factors Enhances Synthetic Hypoxia Biosensors

利用天然缺氧响应因子进行工程反馈可增强合成缺氧生物传感器的性能

Dreyer, Kathleen S; Donahue, Patrick S; Boucher, Jonathan D; Chambers, Katherine M; Ornelas, Marya Y; Edelstein, Hailey I; Leibowitz, Benjamin D; Zhu, Katherine J; Dray, Kate E; Muldoon, Joseph J; Leonard, Joshua N

Exploring structure-function relationships in engineered receptor performance using computational structure prediction

利用计算结构预测探索工程化受体性能中的结构-功能关系

Corcoran, William K; Cosio, Amparo; Edelstein, Hailey I; Leonard, Joshua N

Distinguishing Protein and Gene Delivery Enables Characterization and Bioengineering of Extracellular Vesicle-Adeno-Associated Virus Vectors.

区分蛋白质和基因递送能够表征和生物工程改造细胞外囊泡腺相关病毒载体

Boucher Jonathan D, Stranford Devin M, Edelstein Hailey I, Tullman-Ercek Danielle, Kamat Neha P, Leonard Joshua N

The evolution of synthetic receptor systems

合成受体系统的演变

Manhas, Janvie; Edelstein, Hailey I; Leonard, Joshua N; Morsut, Leonardo

The sound of silence: Transgene silencing in mammalian cell engineering

寂静之声:哺乳动物细胞工程中的转基因沉默

Cabrera, Alan; Edelstein, Hailey I; Glykofrydis, Fokion; Love, Kasey S; Palacios, Sebastian; Tycko, Josh; Zhang, Meng; Lensch, Sarah; Shields, Cara E; Livingston, Mark; Weiss, Ron; Zhao, Huimin; Haynes, Karmella A; Morsut, Leonardo; Chen, Yvonne Y; Khalil, Ahmad S; Wong, Wilson W; Collins, James J; Rosser, Susan J; Polizzi, Karen; Elowitz, Michael B; Fussenegger, Martin; Hilton, Isaac B; Leonard, Joshua N; Bintu, Lacramioara; Galloway, Kate E; Deans, Tara L

Control of mammalian cell-based devices with genetic programming

利用基因编程控制哺乳动物细胞装置

Dray, Kate E; Edelstein, Hailey I; Dreyer, Kathleen S; Leonard, Joshua N

Lack of MTTP Activity in Pluripotent Stem Cell-Derived Hepatocytes and Cardiomyocytes Abolishes apoB Secretion and Increases Cell Stress.

多能干细胞衍生的肝细胞和心肌细胞中 MTTP 活性的缺乏会消除 apoB 分泌并增加细胞应激

Liu Ying, Conlon Donna M, Bi Xin, Slovik Katherine J, Shi Jianting, Edelstein Hailey I, Millar John S, Javaheri Ali, Cuchel Marina, Pashos Evanthia E, Iqbal Jahangir, Hussain M Mahmood, Hegele Robert A, Yang Wenli, Duncan Stephen A, Rader Daniel J, Morrisey Edward E