日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Machine learning reveals sequence and methylation determinants of SaCas9-PAM interactions in bacteria

机器学习揭示细菌中SaCas9-PAM相互作用的序列和甲基化决定因素

Ham, Dalton T; Browne, Tyler S; Zhang, Claire Q; Foo, Gary W; Uruthirapathy, Aathavan S; Gloor, Gregory B; Edgell, David R

Modular determinants of cleavage preference in GIY-YIG nucleases revealed by block-based DNA shuffling and directed evolution

通过基于模块的DNA重组和定向进化揭示GIY-YIG核酸酶切割偏好性的模块化决定因素

Loedige, Kurt W; Hall, Mairwyn A; Ghimirey, Sabin; Stead, Brent E; Edgell, David R

Inflammatory Cytokine Responses to 6 Wks of Increased Dairy Intake in Individuals with Overweight and Obesity-A Randomized Crossover Trial

超重和肥胖个体增加乳制品摄入量 6 周后炎症细胞因子反应——一项随机交叉试验

Prowting, Joel L; Fraschetti, Emily C; Pereira, Tania J; Tucker, Jessica Al; Gagnon, Sara; Cheng, Nicholas; Edgell, Heather; Wright, David C; Klentrou, Panagiota; Perry, Christopher Gr; Josse, Andrea R

Better data for better predictions: data curation improves deep learning for sgRNA/Cas9 prediction

更优质的数据带来更精准的预测:数据整理提升深度学习在sgRNA/Cas9预测中的应用

Browne, Tyler S; Edgell, David R; Gloor, Gregory B

Ku limits RNA-induced innate immunity to allow Alu expansion in primates.

Ku 限制 RNA 诱导的先天免疫,从而允许 Alu 在灵长类动物中扩增。

Zhu Yimeng, Li Angelina, Maji Suvrajit, Lee Brian J, Korn Sophie M, Gertie Jake A, Dorrity Tyler J, Wang Jianhua, Wang Kyle J, Pelletier Amandine, Moakley Daniel F, Kelly Rachel D, Holmes Antony B, Rabadan Raul, Edgell David R, Schild-Poulter Caroline, Modesti Mauro, Steckelberg Anna-Lena, Hendrickson Eric A, Chung Hachung, Zhang Chaolin, Zha Shan

A buffer-tuning strategy to profile domain-specific activity of chimeric I-TevI/CRISPR gene editors in vitro

一种用于体外分析嵌合型 I-TevI/CRISPR 基因编辑器结构域特异性活性的缓冲液调节策略

Loedige, Kurt W; White, Alexa L; McMurrough, Thomas A; Stead, Brent E; Edgell, David R

Genetic Entanglement Enables Ultrastable Biocontainment in the Mammalian Gut

基因纠缠使得哺乳动物肠道内生物体能够超稳定地封闭起来

Foo, Gary W; Uruthirapathy, Aathavan S; Zhang, Claire Q; Batko, Izabela Z; Heinrichs, David E; Edgell, David R

Beyond sex: the effects of testosterone on visuomotor performance in men and women

超越性别:睾酮对男性和女性视觉运动能力的影响

Smeha, Nicole; Gorbet, Diana J; Edgell, Heather; Macpherson, Alison K; Sergio, Lauren E

Associations between age at natural menopause and risk of hypothyroidism among postmenopausal women from the Canadian Longitudinal Study on Aging (CLSA)

加拿大老龄化纵向研究 (CLSA) 中自然绝经年龄与绝经后妇女甲状腺功能减退风险之间的关联

Kesibi, Durmalouk; Rotondi, Michael; Edgell, Heather; Tamim, Hala

Effects of exercise modalities on heart rate recovery and its association with cardiometabolic risk in adolescents with overweight or obesity

运动方式对超重或肥胖青少年心率恢复的影响及其与心血管代谢风险的关系

Pooni, Rubin; Arslanian, Silva; Edgell, Heather; Tamim, Hala; Lee, SoJung; Kuk, Jennifer L