日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Electrophysiological and Proteomic Evidence of Protease-Mediated Pro-nociceptive Signaling in Inflammatory Bowel Disease Patients

炎症性肠病患者中蛋白酶介导的促伤害感受信号的电生理和蛋白质组学证据

期刊:Journal of Neuroscience
影响因子:4
doi:10.1523/JNEUROSCI.0220-25.2025
Wood, Hannah M; Abu Omar, Amal; Baker, Corey C; Alward, Taylor A; Ziegler, Alexander R; Shi, Yun; Nakhle, Rita; Jaramillo-Polanco, Josue; Lopez-Lopez, Cintya; Morissette, Celine; Vanner, Stephen J; Sheth, Prameet M; Edgington Mitchell, Laura E; Reed, David E; Lomax, Alan E
信号转导
炎症/感染
炎症
发表日期：2026
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When Neutrophils Go Rogue: Dysregulated Inflammation in Airway Diseases and Implications for Therapy

中性粒细胞失控：气道疾病中的炎症失调及其治疗意义

期刊:ACS Pharmacology and Translational Science
影响因子:3.7
doi:10.1021/acsptsci.5c00640
Zhu, Yimin; Sardar, Sarmi; Bourke, Jane E; Wark, Peter A B; Edgington-Mitchell, Laura E; Schneider-Futschik, Elena K
中性粒细胞
炎症/感染
Immunology/Inflammation
细胞生物学
炎症
粒细胞
发表日期：2026
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Intralysosomal pathogens differentially influence the proteolytic potential of their niche

溶酶体内病原体对其微环境的蛋白水解潜力产生不同的影响。

期刊:Infection and Immunity
影响因子:2.8
doi:10.1128/iai.00270-25
Bird, Lauren E; Xu, Bangyan; Thomas, David R; McGowan, Erin N S; Newton, Patrice; Scott, Nichollas E; McConville, Malcolm J; Edgington-Mitchell, Laura E; Newton, Hayley J
微生物学
发表日期：2026
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Coxiella burnetii manipulates the lysosomal protease cathepsin B to facilitate intracellular success.

伯氏考克斯体操纵溶酶体蛋白酶组织蛋白酶 B 以促进细胞内感染的成功

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-59283-3
Bird Lauren E, Xu Bangyan, Hobbs Andrew D, Ziegler Alexander R, Scott Nichollas E, Newton Patrice, Thomas David R, Edgington-Mitchell Laura E, Newton Hayley J
细胞生物学
发表日期：2025
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Proteome and Secretome Profiling of the Melanoma-Induced Transition Toward Immune Incompetent Dendritic Cells Reveals Enhanced IDO1, Cathepsin, and Legumain Activity

黑色素瘤诱导的免疫缺陷型树突状细胞转变过程中的蛋白质组和分泌组分析揭示了IDO1、组织蛋白酶和Legumain活性的增强。

期刊:Molecular & Cellular Proteomics
影响因子:5.5
doi:10.1016/j.mcpro.2025.101048
Becker, Anouk M D; Ignacio, Bob J; Dijkstra, Jelmer J; Ziegler, Alexander R; Ramos-Tomillero, Iván; van Dalen, Floris J; Edgington-Mitchell, Laura E; Vermeulen, Michiel; Bonger, Kimberly M; de Vries, I Jolanda M; Verdoes, Martijn
黑色素瘤
IDO
树突状细胞
细胞生物学
树突状细胞
免疫/内分泌
发表日期：2025
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Employing complementary fractionation-based N-terminomics approaches enhances the identification of legumain cleavage events in naïve and inflamed colon tissue.

采用互补的基于分级分离的 N 端组学方法可以增强对正常和发炎结肠组织中 legumain 裂解事件的识别。

期刊:Protein Science
影响因子:5.2
doi:10.1002/pro.70186
Ziegler Alexander R, Parker Benjamin L, Scott Nichollas E, Edgington-Mitchell Laura E
炎症/感染
发表日期：2025
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N-terminomics and proteomics analysis of Calpain-2 reveal key proteolytic processing of metabolic and cell adhesion proteins.

钙蛋白酶-2 的 N 端组学和蛋白质组学分析揭示了代谢和细胞粘附蛋白的关键蛋白水解加工

期刊:Protein Science
影响因子:5.2
doi:10.1002/pro.70144
Kapilan Anjali, Bulluss Mitchell, Ziegler Alexander R, Dabaja Mohamed, Derakhshani Afshin, Anowai Anthonia, Armstrong Victoria, Campden Rhiannon, Young Daniel, Sun Young Joo, Scott Nichollas E, Edgington-Mitchell Laura E, Mahajan Vinit B, Dufour Antoine
代谢
发表日期：2025
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N-terminomics profiling of naïve and inflamed murine colon reveals proteolytic signatures of legumain

幼稚和发炎小鼠结肠的 N 端组学分析揭示了 Legumain 的蛋白水解特征

期刊:Journal of Cellular Physiology
影响因子:4.5
doi:10.1002/jcp.31466
Alexander R Ziegler, Bethany M Anderson, Rocco Latorre, Rachel M McQuade, Antoine Dufour, Brian L Schmidt, Nigel W Bunnett, Nichollas E Scott, Laura E Edgington-Mitchell
免疫
肠炎
发表日期：2025
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Probing the activity of cysteine cathepsins in inflammatory bowel diseases

探究半胱氨酸蛋白酶在炎症性肠病中的活性

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-32489-7
Anderson, Bethany M; Ziegler, Alexander R; Campden, Rhiannon I; Wu, Hongyi; Xu, Bangyan; McQuade, Rachel M; Carbone, Simona E; Poole, Daniel P; Lomax, Alan E; Reed, David E; Vanner, Stephen J; Yates, Robin M; Bunnett, Nigel W; Edgington-Mitchell, Laura E
炎症/感染
炎症
发表日期：2025
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Ion Mobility-Based Enrichment-Free N-Terminomics Analysis Reveals Novel Legumain Substrates in Murine Spleen

基于离子迁移的无富集 N 端组学分析揭示小鼠脾脏中的新型 Legumain 底物

期刊:Molecular & Cellular Proteomics
影响因子:6.1
doi:10.1016/j.mcpro.2024.100714
Alexander R Ziegler, Antoine Dufour, Nichollas E Scott, Laura E Edgington-Mitchell
信号转导
发表日期：2024
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