日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Coxiella burnetii manipulates the lysosomal protease cathepsin B to facilitate intracellular success.

伯氏考克斯体操纵溶酶体蛋白酶组织蛋白酶 B 以促进细胞内感染的成功

Bird Lauren E, Xu Bangyan, Hobbs Andrew D, Ziegler Alexander R, Scott Nichollas E, Newton Patrice, Thomas David R, Edgington-Mitchell Laura E, Newton Hayley J

Employing complementary fractionation-based N-terminomics approaches enhances the identification of legumain cleavage events in naïve and inflamed colon tissue.

采用互补的基于分级分离的 N 端组学方法可以增强对正常和发炎结肠组织中 legumain 裂解事件的识别。

Ziegler Alexander R, Parker Benjamin L, Scott Nichollas E, Edgington-Mitchell Laura E

N-terminomics and proteomics analysis of Calpain-2 reveal key proteolytic processing of metabolic and cell adhesion proteins.

钙蛋白酶-2 的 N 端组学和蛋白质组学分析揭示了代谢和细胞粘附蛋白的关键蛋白水解加工

Kapilan Anjali, Bulluss Mitchell, Ziegler Alexander R, Dabaja Mohamed, Derakhshani Afshin, Anowai Anthonia, Armstrong Victoria, Campden Rhiannon, Young Daniel, Sun Young Joo, Scott Nichollas E, Edgington-Mitchell Laura E, Mahajan Vinit B, Dufour Antoine

N-terminomics profiling of naïve and inflamed murine colon reveals proteolytic signatures of legumain

幼稚和发炎小鼠结肠的 N 端组学分析揭示了 Legumain 的蛋白水解特征

Alexander R Ziegler, Bethany M Anderson, Rocco Latorre, Rachel M McQuade, Antoine Dufour, Brian L Schmidt, Nigel W Bunnett, Nichollas E Scott, Laura E Edgington-Mitchell

Probing the activity of cysteine cathepsins in inflammatory bowel diseases

探究半胱氨酸蛋白酶在炎症性肠病中的活性

Anderson, Bethany M; Ziegler, Alexander R; Campden, Rhiannon I; Wu, Hongyi; Xu, Bangyan; McQuade, Rachel M; Carbone, Simona E; Poole, Daniel P; Lomax, Alan E; Reed, David E; Vanner, Stephen J; Yates, Robin M; Bunnett, Nigel W; Edgington-Mitchell, Laura E

Ion Mobility-Based Enrichment-Free N-Terminomics Analysis Reveals Novel Legumain Substrates in Murine Spleen

基于离子迁移的无富集 N 端组学分析揭示小鼠脾脏中的新型 Legumain 底物

Alexander R Ziegler, Antoine Dufour, Nichollas E Scott, Laura E Edgington-Mitchell

Protease-activated receptors in health and disease

健康和疾病中的蛋白酶激活受体

Peach, Chloe J; Edgington-Mitchell, Laura E; Bunnett, Nigel W; Schmidt, Brian L

Chemical Tools to Image the Activity of PAR-Cleaving Proteases

用于成像PAR裂解蛋白酶活性的化学工具

Lee, Irene Y; Tantisirivat, Piyapa; Edgington-Mitchell, Laura E

Ubiquitin-like protein 3 (UBL3) is required for MARCH ubiquitination of major histocompatibility complex class II and CD86

泛素样蛋白 3 (UBL3) 是 MARCH 泛素化主要组织相容性复合体 II 类和 CD86 所必需的

Haiyin Liu, Kayla R Wilson, Ashley M Firth, Christophe Macri, Patrick Schriek, Annabelle B Blum, Javiera Villar, Samuel Wormald, Mitch Shambrook, Bangyan Xu, Hui Jing Lim, Hamish E G McWilliam, Andrew F Hill, Laura E Edgington-Mitchell, Irina Caminschi, Mireille H Lahoud, Elodie Segura, Marco J Hero

Treating Parkinson's Disease via Activation of BDNF/TrkB Signaling Pathways and Inhibition of Delta-Secretase

通过激活 BDNF/TrkB 信号通路和抑制 Delta-Secretase 治疗帕金森病

Seong Su Kang #, Zhourui Wu #, Xia Liu, Laura Edgington-Mitchell, Keqiang Ye