文献库，生知库 | 链接生命科学的每一步

日期影响因子

Mapping the genetic landscape establishing a tumor immune microenvironment favorable for anti-PD-1 response

绘制构建有利于抗PD-1反应的肿瘤免疫微环境的遗传图谱

期刊:Cell Reports

影响因子:7.5

doi:10.1016/j.celrep.2025.115698

Daniel A Skelly ，John P Graham ，Mingshan Cheng ，Mayuko Furuta ，Andrew Walter ，Thomas A Stoklasek ，Hongyuan Yang ，Timothy M Stearns ，Olivier Poirion ，Ji-Gang Zhang ，Jessica D S Grassmann ，Diane Luo ，William F Flynn ，Elise T Courtois ，Chih-Hao Chang ，David V Serreze ，Francesca Menghi ，Laura G Reinholdt ，Edison T Liu

免疫/内分泌

发表日期：2025

文献求助收藏

High-throughput deconvolution of 3D organoid dynamics at cellular resolution for cancer pharmacology with Cellos

使用 Cellos 对细胞分辨率的 3D 类器官动力学进行高通量反卷积，用于癌症药理学研究

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-023-44162-6

Patience Mukashyaka #, Pooja Kumar #, David J Mellert, Shadae Nicholas, Javad Noorbakhsh, Mattia Brugiolo, Elise T Courtois, Olga Anczukow, Edison T Liu, Jeffrey H Chuang

发表日期：2023

文献求助收藏

Cellos: High-throughput deconvolution of 3D organoid dynamics at cellular resolution for cancer pharmacology

Cellos：以细胞分辨率对 3D 类器官动力学进行高通量反卷积，用于癌症药理学

doi:10.1101/2023.03.03.531019

Patience Mukashyaka, Pooja Kumar, David J Mellert, Shadae Nicholas, Javad Noorbakhsh, Mattia Brugiolo, Olga Anczukow, Edison T Liu, Jeffrey H Chuang

细胞生物学

发表日期：2023

文献求助收藏

Lipid-laden lung mesenchymal cells foster breast cancer metastasis via metabolic reprogramming of tumor cells and natural killer cells

富含脂质的肺间充质细胞通过对肿瘤细胞和自然杀伤细胞的代谢重编程促进乳腺癌转移。

期刊:Cell Metabolism

影响因子:27.7

doi:10.1016/j.cmet.2022.11.003

Zheng Gong ，Qing Li ，Jiayuan Shi ，Edison T Liu ，Leonard D Shultz ，Guangwen Ren

细胞生物学

代谢重编程

自然杀伤细胞

发表日期：2022

文献求助收藏

Genomic and epigenomic BRCA alterations predict adaptive resistance and response to platinum-based therapy in patients with triple-negative breast and ovarian carcinomas

基因组和表观基因组 BRCA 变异可预测三阴性乳腺癌和卵巢癌患者对铂类治疗的适应性耐药性和反应

期刊:Science Translational Medicine

影响因子:15.8

doi:10.1126/scitranslmed.abn1926

Francesca Menghi, Kalyan Banda, Pooja Kumar, Robert Straub, Lacey Dobrolecki, Isabel V Rodriguez, Susan E Yost, Harshpreet Chandok, Marc R Radke, George Somlo, Yuan Yuan, Michael T Lewis, Elizabeth M Swisher, Edison T Liu

发表日期：2022

文献求助收藏

FANCM regulates repair pathway choice at stalled replication forks

FANCM 调节停滞复制叉处的修复途径选择

期刊:Molecular Cell

影响因子:14.5

doi:10.1016/j.molcel.2021.03.044

Arvind Panday, Nicholas A Willis, Rajula Elango, Francesca Menghi, Erin E Duffey, Edison T Liu, Ralph Scully

发表日期：2021

文献求助收藏

Chromatin topology reorganization and transcription repression by PML-RARα in acute promyeloid leukemia

急性早幼粒细胞白血病中 PML-RARα 的染色质拓扑重组和转录抑制

期刊:Genome Biology

影响因子:10.1

doi:10.1186/s13059-020-02030-2

Ping Wang, Zhonghui Tang, Byoungkoo Lee, Jacqueline Jufen Zhu, Liuyang Cai, Przemyslaw Szalaj, Simon Zhongyuan Tian, Meizhen Zheng, Dariusz Plewczynski, Xiaoan Ruan, Edison T Liu, Chia-Lin Wei, Yijun Ruan

发表日期：2020

文献求助收藏

Picky comprehensively detects high-resolution structural variants in nanopore long reads

Picky 全面检测纳米孔长读长中的高分辨率结构变异

期刊:Nature Methods

影响因子:36.1

doi:10.1038/s41592-018-0002-6

Liang Gong, Chee-Hong Wong, Wei-Chung Cheng, Harianto Tjong, Francesca Menghi, Chew Yee Ngan, Edison T Liu, Chia-Lin Wei

发表日期：2018

文献求助收藏

Humanized mice in studying efficacy and mechanisms of PD-1-targeted cancer immunotherapy

人源化小鼠用于研究 PD-1 靶向癌症免疫治疗的疗效和机制

期刊:FASEB Journal

影响因子:4.4

doi:10.1096/fj.201700740R

Minan Wang, Li-Chin Yao, Mingshan Cheng, Danying Cai, Jan Martinek, Chong-Xian Pan, Wei Shi, Ai-Hong Ma, Ralph W De Vere White, Susan Airhart, Edison T Liu, Jacques Banchereau, Michael A Brehm, Dale L Greiner, Leonard D Shultz, Karolina Palucka, James G Keck

发表日期：2018

文献求助收藏

Mechanism of tandem duplication formation in BRCA1-mutant cells

BRCA1 突变细胞中串联重复形成的机制

影响因子:50.5

doi:10.1038/nature24477

Nicholas A Willis, Richard L Frock, Francesca Menghi, Erin E Duffey, Arvind Panday, Virginia Camacho, E Paul Hasty, Edison T Liu, Frederick W Alt, Ralph Scully

细胞生物学

发表日期：2017

文献求助收藏