日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Naturally-aged microglia exhibit phagocytic dysfunction accompanied by gene expression changes reflective of underlying neurologic disease

自然衰老的小胶质细胞表现出吞噬功能障碍,并伴有反映潜在神经系统疾病的基因表达变化

Alyssa L Thomas, Maria A Lehn, Edith M Janssen, David A Hildeman, Claire A Chougnet

Promotion of Anti-Tuberculosis Macrophage Activity by L-Arginine in the Absence of Nitric Oxide

L-精氨酸在缺乏一氧化氮的情况下促进抗结核巨噬细胞活性

Melanie C McKell ,Rebecca R Crowther ,Stephanie M Schmidt ,Michelle C Robillard ,Rachel Cantrell ,Maria A Lehn ,Edith M Janssen ,Joseph E Qualls

Immune Checkpoint Inhibitors Regulate K+ Channel Activity in Cytotoxic T Lymphocytes of Head and Neck Cancer Patients

免疫检查点抑制剂调节头颈癌患者细胞毒性 T 淋巴细胞的 K+ 通道活性

Vaibhavkumar S Gawali, Ameet A Chimote, Hannah S Newton, Manuel G Feria-Garzón, Martina Chirra, Edith M Janssen, Trisha M Wise-Draper, Laura Conforti

CD244 represents a new therapeutic target in head and neck squamous cell carcinoma

CD244 代表头颈部鳞状细胞癌的新治疗靶点

Laura Agresta, Maria Lehn, Kristin Lampe, Rachel Cantrell, Cassandra Hennies, Sara Szabo, Trisha Wise-Draper, Laura Conforti, Kasper Hoebe, Edith M Janssen

PD1 blockade enhances K+ channel activity, Ca2+ signaling, and migratory ability in cytotoxic T lymphocytes of patients with head and neck cancer

PD1 阻断可增强头颈癌患者细胞毒性 T 淋巴细胞的 K+ 通道活性、Ca2+ 信号传导和迁移能力

Hannah S Newton #, Vaibhavkumar S Gawali #, Ameet A Chimote #, Maria A Lehn, Sarah M Palackdharry, Benjamin H Hinrichs, Roman Jandarov, David Hildeman, Edith M Janssen, Trisha M Wise-Draper, Laura Conforti

Loss of GTPase of immunity-associated protein 5 (Gimap5) promotes pathogenic CD4+ T-cell development and allergic airway disease

免疫相关蛋白 5 (Gimap5) 的 GTPase 缺失会促进致病性 CD4+ T 细胞发育和过敏性呼吸道疾病

Andrew R Patterson, Paige Bolcas, Kristin Lampe, Rachel Cantrell, Brandy Ruff, Ian Lewkowich, Simon P Hogan, Edith M Janssen, Jack Bleesing, Gurjit K Khurana Hershey, Kasper Hoebe

Defective transcription elongation in a subset of cancers confers immunotherapy resistance

部分癌症中转录延伸缺陷会导致免疫疗法耐药。

Vishnu Modur,Navneet Singh,Vakul Mohanty,Eunah Chung,Belal Muhammad,Kwangmin Choi,Xiaoting Chen,Kashish Chetal,Nancy Ratner,Nathan Salomonis,Matthew T Weirauch,Susan Waltz,Gang Huang,Lisa Privette-Vinnedge,Joo-Seop Park,Edith M Janssen,Kakajan Komurov

STING-mediated DNA sensing promotes antitumor and autoimmune responses to dying cells

STING 介导的 DNA 传感促进对死亡细胞的抗肿瘤和自身免疫反应

Jared Klarquist, Cassandra M Hennies, Maria A Lehn, Rachel A Reboulet, Sonia Feau, Edith M Janssen

Dendritic cell programming by cytomegalovirus stunts naive T cell responses via the PD-L1/PD-1 pathway

巨细胞病毒通过PD-L1/PD-1通路对树突状细胞进行编程,从而抑制初始T细胞反应。

Chris A Benedict ,Andrea Loewendorf, Zacarias Garcia, Bruce R Blazar, Edith M Janssen

CD4 cell-secreted, posttranslationally modified cytokine GIF suppresses Th2 responses by inhibiting the initiation of IL-4 production

CD4 细胞分泌的翻译后修饰细胞因子 GIF 通过抑制 IL-4 产生的启动来抑制 Th2 反应

Misa Kim-Saijo, Edith M Janssen, Katsuji Sugie