Structure-Guided Design of ISOX-DUAL-Based Degraders Targeting BRD4 and CBP/EP300: A Case of Degrader Collapse.
基于 ISOX-DUAL 的结构导向降解剂设计：针对 BRD4 和 CBP/EP300 的降解剂崩溃案例
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c00395
Edmonds Anthony K, Balourdas Dimitrios-Ilias, Marsh Graham P, Felix Robert, Brasher Bradley, Cooper Jeff, Graber-Feesl Cari, Kollareddy Madhu, Malik Karim, Stewart Helen, Chevassut Timothy J T, Lineham Ella, Morley Simon, Fedorov Oleg, Bennett James, Rajasekaran Mohan B, Ojeda Samuel, Harrison Drew A, Ott Christopher J, Joerger Andreas C, Maple Hannah J, Spencer John
