日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Immunophenotypic correlates of sustained MRD negativity in patients with multiple myeloma

多发性骨髓瘤患者持续 MRD 阴性的免疫表型相关性

David G Coffey, Francesco Maura, Edgar Gonzalez-Kozlova, J Javier Diaz-Mejia, Ping Luo, Yong Zhang, Yuexin Xu, Edus H Warren, Travis Dawson, Brian Lee, Hui Xie, Eric Smith, Amanda Ciardiello, Hearn J Cho, Adeeb Rahman, Seunghee Kim-Schulze, Benjamin Diamond, Alexander Lesokhin #, Dickran Kazandjian 

Therapeutic targeting of tumor spheroids in a 3D microphysiological renal cell carcinoma-on-a-chip system

3D 微生理肾细胞癌芯片系统中肿瘤球体的治疗靶向

Chris P Miller, Megan Fung, Carla A Jaeger-Ruckstuhl, Yuexin Xu, Edus H Warren, Shreeram Akilesh, Scott S Tykodi

CD4 and CD8 co-receptors modulate functional avidity of CD1b-restricted T cells

CD4 和 CD8 共受体调节 CD1b 限制性 T 细胞的功能亲和力

Charlotte A James, Yuexin Xu, Melissa S Aguilar, Lichen Jing, Erik D Layton, Martine Gilleron, Adriaan J Minnaard, Thomas J Scriba, Cheryl L Day, Edus H Warren, David M Koelle, Chetan Seshadri

Integrated TCR repertoire analysis and single-cell transcriptomic profiling of tumor-infiltrating T cells in renal cell carcinoma identifies shared and tumor-restricted expanded clones with unique phenotypes

肾细胞癌中肿瘤浸润 T 细胞的综合 TCR 库分析和单细胞转录组分析可识别具有独特表型的共享和肿瘤限制性扩增克隆

Yuexin Xu, Alicia J Morales, Andrea M H Towlerton, Shreeram Akilesh, Chris P Miller, Scott S Tykodi, Edus H Warren

RNA helicase, DDX3X, is actively recruited to sites of DNA damage in live cells

RNA 解旋酶 DDX3X 被积极招募到活细胞中的 DNA 损伤位点

Michael J Cargill, Alicia Morales, Shashidhar Ravishankar, Edus H Warren

Preclinical development of T-cell receptor-engineered T-cell therapy targeting the 5T4 tumor antigen on renal cell carcinoma

针对肾细胞癌 5T4 肿瘤抗原的 T 细胞受体工程化 T 细胞疗法的临床前开发

Yuexin Xu, Alicia J Morales, Michael J Cargill, Andrea M H Towlerton, David G Coffey, Edus H Warren, Scott S Tykodi

Cyclin-A1 represents a new immunogenic targetable antigen expressed in acute myeloid leukemia stem cells with characteristics of a cancer-testis antigen

细胞周期蛋白 A1 是一种新的免疫原性靶向抗原,在急性髓系白血病干细胞中表达,具有癌睾丸抗原的特征

Sebastian Ochsenreither, Ravindra Majeti, Thomas Schmitt, Derek Stirewalt, Ulrich Keilholz, Keith R Loeb, Brent Wood, Yongiae E Choi, Marie Bleakley, Edus H Warren, Michael Hudecek, Yoshiki Akatsuka, Irving L Weissman, Philip D Greenberg

Epigenetic modulation to enable antigen-specific T-cell therapy of colorectal cancer

表观遗传调控使结直肠癌抗原特异性T细胞治疗成为可能

Jeffrey Chou, Lilien N Voong, Christie L Mortales, Andrea M H Towlerton, Seth M Pollack, Xiaoji Chen, Cassian Yee, Paul F Robbins, Edus H Warren

CD8+ T-cell clones specific for the 5T4 antigen target renal cell carcinoma tumor-initiating cells in a murine xenograft model

针对 5T4 抗原的 CD8+ T 细胞克隆在小鼠异种移植模型中靶向肾细胞癌肿瘤起始细胞

Scott S Tykodi, Shoko Satoh, Janise D Deming, Jeffrey Chou, Richard Harrop, Edus H Warren

Activation and expansion of CD8(+) T effector cells in patients with chronic graft-versus-host disease

慢性移植物抗宿主病患者CD8(+)T效应细胞的激活和扩增

Bryan M Grogan, Laura Tabellini, Barry Storer, Tara E Bumgarner, Claudia C Astigarraga, Mary E D Flowers, Stephanie J Lee, Paul J Martin, Edus H Warren, John A Hansen