日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

High-Throughput Flow Cytometry Drug Combination Discovery with Novel Synergy Analysis Software, SynScreen

利用新型协同分析软件 SynScreen 进行高通量流式细胞术药物组合发现

Perez, Dominique R; Edwards, Bruce S; Sklar, Larry A; Chigaev, Alexandre

Line-Focused Optical Excitation of Parallel Acoustic Focused Sample Streams for High Volumetric and Analytical Rate Flow Cytometry

用于高体积和高分析速率流式细胞术的平行声聚焦样品流的线聚焦光学激发

Kalb, Daniel M; Fencl, Frank A; Woods, Travis A; Swanson, August; Maestas, Gian C; Juárez, Jaime J; Edwards, Bruce S; Shreve, Andrew P; Graves, Steven W

Flow Cytometry: Impact on Early Drug Discovery

流式细胞术:对早期药物发现的影响

Edwards, Bruce S; Sklar, Larry A

Selective chemical inhibition of agr quorum sensing in Staphylococcus aureus promotes host defense with minimal impact on resistance

选择性化学抑制金黄色葡萄球菌中的agr群体感应可增强宿主防御能力,且对耐药性的影响极小。

Sully, Erin K; Malachowa, Natalia; Elmore, Bradley O; Alexander, Susan M; Femling, Jon K; Gray, Brian M; DeLeo, Frank R; Otto, Michael; Cheung, Ambrose L; Edwards, Bruce S; Sklar, Larry A; Horswill, Alexander R; Hall, Pamela R; Gresham, Hattie D

Elastomeric negative acoustic contrast particles for affinity capture assays

用于亲和捕获试验的弹性负声学对比颗粒

Cushing, Kevin W; Piyasena, Menake E; Carroll, Nick J; Maestas, Gian C; López, Beth Ann; Edwards, Bruce S; Graves, Steven W; López, Gabriel P

Rapid scanning structure-activity relationships in combinatorial data sets: identification of activity switches

快速扫描组合数据集中的构效关系:活性开关的识别

Medina-Franco, José L; Edwards, Bruce S; Pinilla, Clemencia; Appel, Jon R; Giulianotti, Marc A; Santos, Radleigh G; Yongye, Austin B; Sklar, Larry A; Houghten, Richard A

Selective agonists and antagonists of formylpeptide receptors: duplex flow cytometry and mixture-based positional scanning libraries

甲酰肽受体的选择性激动剂和拮抗剂:双重流式细胞术和基于混合物的定位扫描库

Pinilla, Clemencia; Edwards, Bruce S; Appel, Jon R; Yates-Gibbins, Tina; Giulianotti, Marc A; Medina-Franco, Jose L; Young, Susan M; Santos, Radleigh G; Sklar, Larry A; Houghten, Richard A

Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry

利用基于流式细胞术的多重筛选方法鉴定酵母TORC1小分子抑制剂

Chen, Jun; Young, Susan M; Allen, Chris; Seeber, Andrew; Péli-Gulli, Marie-Pierre; Panchaud, Nicolas; Waller, Anna; Ursu, Oleg; Yao, Tuanli; Golden, Jennifer E; Strouse, J Jacob; Carter, Mark B; Kang, Huining; Bologa, Cristian G; Foutz, Terry D; Edwards, Bruce S; Peterson, Blake R; Aubé, Jeffrey; Werner-Washburne, Margaret; Loewith, Robbie J; De Virgilio, Claudio; Sklar, Larry A

Simultaneous in vitro molecular screening of protein-peptide interactions by flow cytometry, using six Bcl-2 family proteins as examples.

利用流式细胞术同时对六种 Bcl-2 家族蛋白进行蛋白质-肽相互作用的体外分子筛选

Simons Peter C, Young Susan M, Carter Mark B, Waller Anna, Zhai Dayong, Reed John C, Edwards Bruce S, Sklar Larry A

High-throughput screen for the chemical inhibitors of antiapoptotic bcl-2 family proteins by multiplex flow cytometry

利用多重流式细胞术高通量筛选抗凋亡bcl-2家族蛋白的化学抑制剂

Curpan, Ramona F; Simons, Peter C; Zhai, Dayong; Young, Susan M; Carter, Mark B; Bologa, Cristian G; Oprea, Tudor I; Satterthwait, Arnold C; Reed, John C; Edwards, Bruce S; Sklar, Larry A