日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

EWS-WT1 fusion isoforms establish oncogenic programs and therapeutic vulnerabilities in desmoplastic small round cell tumors

EWS-WT1融合亚型在促纤维增生性小圆细胞肿瘤中建立致癌程序和治疗弱点

Gaylor Boulay #,Liliane C Broye #,Rui Dong #,Sowmya Iyer,Rajendran Sanalkumar,Yu-Hang Xing,Rémi Buisson,Shruthi Rengarajan,Beverly Naigles,Benoît Duc,Angela Volorio,Mary E Awad,Raffaele Renella,Ivan Chebib,G Petur Nielsen,Edwin Choy,Gregory M Cote,Lee Zou,Igor Letovanec,Ivan Stamenkovic,Miguel N Rivera,Nicolò Riggi

Highly connected 3D chromatin networks established by an oncogenic fusion protein shape tumor cell identity

致癌融合蛋白建立的高度连通的三维染色质网络塑造肿瘤细胞身份

Rajendran Sanalkumar, Rui Dong, Lukuo Lee, Yu-Hang Xing, Sowmya Iyer, Igor Letovanec, Stefano La Rosa, Giovanna Finzi, Elettra Musolino, Roberto Papait, Ivan Chebib, G Petur Nielsen, Raffaele Renella, Gregory M Cote, Edwin Choy, Martin Aryee, Kimberly Stegmaier, Ivan Stamenkovic, Miguel N Rivera, Ni

Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma

免疫和遗传机制的拮抗作用塑造了滑膜肉瘤的致癌程序

Livnat Jerby-Arnon # ,Cyril Neftel # ,Marni E Shore ,Hannah R Weisman ,Nathan D Mathewson ,Matthew J McBride ,Brian Haas ,Benjamin Izar ,Angela Volorio ,Gaylor Boulay ,Luisa Cironi ,Alyssa R Richman ,Liliane C Broye ,Joseph M Gurski ,Christina C Luo ,Ravindra Mylvaganam ,Lan Nguyen ,Shaolin Mei ,Johannes C Melms ,Christophe Georgescu ,Ofir Cohen ,Jorge E Buendia-Buendia ,Asa Segerstolpe ,Malika Sud ,Michael S Cuoco ,Danny Labes ,Simon Gritsch ,Daniel R Zollinger ,Nicole Ortogero ,Joseph M Beechem ,G Petur Nielsen ,Ivan Chebib ,Tu Nguyen-Ngoc ,Michael Montemurro ,Gregory M Cote ,Edwin Choy ,Igor Letovanec ,Stéphane Cherix ,Nikhil Wagle ,Peter K Sorger ,Alex B Haynes ,John T Mullen ,Ivan Stamenkovic ,Miguel N Rivera ,Cigall Kadoch ,Kai W Wucherpfennig ,Orit Rozenblatt-Rosen ,Mario L Suvà ,Nicolò Riggi ,Aviv Regev

LIN28B Underlies the Pathogenesis of a Subclass of Ewing Sarcoma

LIN28B 是尤文氏肉瘤亚类发病机制的基础

Tugba Keskin, Arnaud Bakaric, Patricia Waszyk, Gaylor Boulay, Matteo Torsello, Sandrine Cornaz-Buros, Nadja Chevalier, Thibaud Geiser, Patricia Martin, Angela Volorio, Sowmya Iyer, Anupriya Kulkarni, Igor Letovanec, Stéphane Cherix, Gregory M Cote, Edwin Choy, Antonia Digklia, Michael Montemurro, Iv

LIN28B Underlies the Pathogenesis of a Subclass of Ewing Sarcoma LIN28B Control of EWS-FLI1 Stability

LIN28B 是尤文氏肉瘤亚类发病机制的基础 LIN28B 控制 EWS-FLI1 的稳定性

Tugba Keskin, Arnaud Bakaric, Patricia Waszyk, Gaylor Boulay, Matteo Torsello, Sandrine Cornaz-Buros, Nadja Chevalier, Thibaud Geiser, Patricia Martin, Angela Volorio, Sowmya Iyer, Anupriya Kulkarni, Igor Letovanec, Stéphane Cherix, Gregory M Cote, Edwin Choy, Antonia Digklia, Michael Montemurro, Iv

Expression and Therapeutic Potential of SOX9 in Chordoma

SOX9 在脊索瘤中的表达和治疗潜力

Hua Chen, Cassandra C Garbutt, Dimitrios Spentzos, Edwin Choy, Francis J Hornicek, Zhenfeng Duan

miR-15b modulates multidrug resistance in human osteosarcoma in vitro and in vivo

miR-15b 在体内和体外调节人类骨肉瘤的多药耐药性

Zhenfeng Duan, Yan Gao, Jacson Shen, Edwin Choy, Gregory Cote, David Harmon, Karen Bernstein, Santiago Lozano-Calderon, Henry Mankin, Francis J Hornicek

Androgen receptor is a potential novel prognostic marker and oncogenic target in osteosarcoma with dependence on CDK11

雄激素受体是骨肉瘤中潜在的新型预后标志物和致癌靶点,依赖于 CDK11

Yunfei Liao, Slim Sassi, Stefan Halvorsen, Yong Feng, Jacson Shen, Yan Gao, Gregory Cote, Edwin Choy, David Harmon, Henry Mankin, Francis Hornicek, Zhenfeng Duan

Mocetinostat combined with gemcitabine for the treatment of leiomyosarcoma: Preclinical correlates

莫西替诺特联合吉西他滨治疗平滑肌肉瘤:临床前相关性

Gonzalo Lopez, Danielle Braggio, Abeba Zewdu, Lucia Casadei, Kara Batte, Hemant Kumar Bid, David Koller, Peter Yu, Obiajulu Hans Iwenofu, Anne Strohecker, Edwin Choy, Dina Lev, Raphael Pollock

Targeting DYRK1B suppresses the proliferation and migration of liposarcoma cells

靶向 DYRK1B 抑制脂肪肉瘤细胞的增殖和迁移

Hua Chen, Jacson Shen, Edwin Choy, Francis J Hornicek, Aijun Shan, Zhenfeng Duan