日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Functional Analysis of a Novel HNF4A Variant Identified in a Patient With MODY1

对 MODY1 患者中发现的新型 HNF4A 变体进行功能分析

Shuntaro Morikawa, Hui Ling Ko, Ee Chee Ren, Kazuya Hara, Naoya Kaneko, Nozomi Hishimura, Akie Nakamura, Atsushi Manabe

cccDNA-Targeted Drug Screen Reveals a Class of Antihistamines as Suppressors of HBV Genome Levels

cccDNA 靶向药物筛选揭示一类抗组胺药可作为 HBV 基因组水平的抑制剂

Ee Chee Ren, Nicole Ziyi Zhuo, Zhi Yi Goh, Isabelle Bonne, Benoît Malleret, Hui Ling Ko

HNF4α Combinatorial Isoform Heterodimers Activate Distinct Gene Targets that Differ from Their Corresponding Homodimers

HNF4α 组合异构体异二聚体激活与其相应同二聚体不同的不同基因靶标

Hui Ling Ko, Ziyi Zhuo, Ee Chee Ren

Crystal structure of suboptimal viral fragments of Epstein Barr Virus Rta peptide-HLA complex that stimulate CD8 T cell response

刺激 CD8 T 细胞反应的 Epstein Barr 病毒 Rta 肽-HLA 复合物的次优病毒片段的晶体结构

Xuelu Huan, Ziyi Zhuo, Ziwei Xiao, Ee Chee Ren

Nonstimulatory peptide-MHC enhances human T-cell antigen-specific responses by amplifying proximal TCR signaling

非刺激性肽-MHC 通过放大近端 TCR 信号增强人类 T 细胞抗原特异性反应

Xiang Zhao, Shvetha Sankaran, Jiawei Yap, Chien Tei Too, Zi Zong Ho, Garry Dolton, Mateusz Legut, Ee Chee Ren, Andrew K Sewell, Antonio Bertoletti, Paul A MacAry, Joanna Brzostek, Nicholas R J Gascoigne

Influenza A Virus Facilitates Its Infectivity by Activating p53 to Inhibit the Expression of Interferon-Induced Transmembrane Proteins

甲型流感病毒通过激活 p53 抑制干扰素诱导的跨膜蛋白表达来增强其传染性

Bei Wang, Tze Hau Lam, Mun Kuen Soh, Zhiyong Ye, Jinmiao Chen, Ee Chee Ren

Intrahaplotypic Variants Differentiate Complex Linkage Disequilibrium within Human MHC Haplotypes

单倍型内变异区分人类 MHC 单倍型内的复杂连锁不平衡

Tze Hau Lam, Matthew Zirui Tay, Bei Wang, Ziwei Xiao, Ee Chee Ren

The immunodominant influenza A virus M158-66 cytotoxic T lymphocyte epitope exhibits degenerate class I major histocompatibility complex restriction in humans

免疫显性甲型流感病毒 M158-66 细胞毒性 T 淋巴细胞表位在人类中表现出退化的 I 类主要组织相容性复合体限制

Joanna A L Choo, Jingxian Liu, Xinyu Toh, Gijsbert M Grotenbreg, Ee Chee Ren

p53 increases MHC class I expression by upregulating the endoplasmic reticulum aminopeptidase ERAP1

p53 通过上调内质网氨基肽酶 ERAP1 来增加 MHC I 类表达

Bei Wang, Dandan Niu, Liyun Lai, Ee Chee Ren

hnRNP K suppresses apoptosis independent of p53 status by maintaining high levels of endogenous caspase inhibitors

hnRNP K 通过维持高水平的内源性 caspase 抑制剂来抑制不依赖于 p53 状态的细胞凋亡

Ziwei Xiao, Hui Ling Ko, Ee Hui Goh, Bei Wang, Ee Chee Ren