Functional Engagement of the PD-1/PD-L1 Complex But Not PD-L1 Expression Is Highly Predictive of Patient Response to Immunotherapy in Non-Small-Cell Lung Cancer
PD-1/PD-L1复合物的功能性激活而非PD-L1表达是预测非小细胞肺癌患者对免疫疗法反应的重要指标。
期刊:Journal of Clinical Oncology
影响因子:41.9
doi:10.1200/JCO.22.01748
Sánchez-Magraner, Lissete; Gumuzio, Juan; Miles, James; Quimi, Nicole; Martínez Del Prado, Purificación; Abad-Villar, María Teresa; Pikabea, Fernando; Ortega, Laura; Etxezarraga, Carmen; Martín-Algarra, Salvador; Lozano, María D; Saiz-Camin, Mónica; Egurrola-Izquierdo, Mikel; Barredo-Santamaría, Inmaculada; Saiz-López, Alberto; Gomez-Mediavilla, Jenifer; Segues-Merino, Nerea; Juaristi-Abaunz, María Aranzazu; Urruticoechea, Ander; Geraedts, Erica J; van Elst, Kim; Claessens, Niels J M; Italiano, Antoine; Applebee, Christopher J; Del Castillo, Sandra; Evans, Charles; Aguirre, Fernando; Parker, Peter J; Calleja, Véronique
肺癌
肿瘤
肿瘤免疫
PD-L1
细胞生物学
PD-1
免疫/内分泌
