日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Differential downstream signaling in microglia lacking Alzheimer's-related TREM2 or its adaptor TYROBP/DAP12

缺乏阿尔茨海默病相关TREM2或其衔接蛋白TYROBP/DAP12的小胶质细胞中下游信号传导的差异

Farias Quipildor, Gabriela E; Belfiore, Ramona; Althobaiti, Khaled; Najarzadeh, Zahra; Glabe, Charles; Readhead, Benjamin P; Gandy, Sam; Salton, Stephen R J; Ehrlich, Michelle E

QuadST identifies cell-cell interaction-changed genes in spatially resolved transcriptomics data

QuadST利用空间分辨转录组学数据识别细胞间相互作用改变的基因

Song, Xiaoyu; Shang, Yuqing; Ehrlich, Michelle E; Roussos, Panos; Yuan, Guo-Cheng; Wang, Pei

Characterization of human cytomegalovirus infection dynamics in human microglia.

人类巨细胞病毒感染人类小胶质细胞动力学的特征分析

Nuevalos Guaita Marcos, Jimoh Tajudeen O, Barrall Emma B, Atanasoff Kristina E, Ehrlich Michelle E, Gandy Sam, García-Ríos Estéfani, Perez Romero Pilar, Duty J Andrew, Tortorella Domenico

Cerulenin partially corrects the disrupted developmental transcriptomic signature in Huntington's disease striatal medium spiny neurons.

塞鲁宁可部分纠正亨廷顿病纹状体中型棘状神经元发育转录组特征的紊乱

Galicia Aguirre Carlos, Tshilenge Kizito-Tshitoko, Battistoni Elena, Lopez-Ramirez Alejandro, Naphade Swati, Perez Kevin, Gerencser Akos A, Song Sicheng, Mooney Sean D, Melov Simon, Ehrlich Michelle E, Ellerby Lisa M

Endogenously generated Dutch-type Aβ nonfibrillar aggregates dysregulate presynaptic neurotransmission in the absence of detectable inflammation

内源性生成的荷兰型Aβ非纤维聚集体在没有可检测到的炎症的情况下会扰乱突触前神经传递。

Castranio, Emilie L; Varghese, Merina; Argyrousi, Elentina K; Tripathi, Kuldeep; Söderberg, Linda; Bresnahan, Erin; Lerner, David; Garretti, Francesca; Zhang, Hong; van de Loo, Jonathan; Stimpson, Cheryl D; Talty, Ronan; Glabe, Charles; Levy, Efrat; Wang, Minghui; Ilkov, Marjan; Zhang, Bin; Lannfelt, Lars; Guérin, Brigitte; Lubell, William D; Rahimipour, Shai; Dickstein, Dara L; Gandy, Sam; Arancio, Ottavio; Ehrlich, Michelle E

EPCO-61. INTEGRATIVE MULTI-OMICS ANALYSIS OF GLIOBLASTOMA IDENTIFIES DRIVERS OF TUMOR AGGRESSION AND RECURRENCE

EPCO-61. 胶质母细胞瘤的整合多组学分析揭示肿瘤侵袭性和复发的驱动因素

Wang, Erming; Pan, Allen L; Bagchi, Pritha; Ranjaraju, Srikant; Seyfried, Nicholas T; Ehrlich, Michelle E; Salton, Stephen R; Zhang, Bin; Bahcheli, Alexander; Slobodyanyuk, Mykhaylo; Min, Hyun-Kee; Zuzarte, Philip; Simpson, Jared; Huang, Xi; Das, Sunit; Reimand, Jüri

IGF1R VARIANT R407H PREVENTS COGNITIVE IMPAIRMENT AND NEUROINFLAMMATION IN CRISPR MICE WITH AAV AB42 AND PTAU

IGF1R 变体 R407H 可预防经 AAV AB42 和 PTAU 处理的 CRISPR 小鼠的认知障碍和神经炎症

Zhu, Xiaodong; Haure-Mirande, Jean-Vianney; Bicak, Mesude; Dong, Pengfei; Kruglikov, Ilya; Al-Subaie, Aisha; Fossati, Valentina; Noggle, Scott; Gandy, Sam; Ehrlich, Michelle E; Meyyazhagan, Arun; Basavaraju, Preethi; Miele, Marialuisa; Kawarai, Toshitaka; Panza, Emanuele; Orlacchio, Antonio; Park, Joo Young; Wezeman, Jackson; Mangalindan, Ruby Sue; Ladiges, Warren

miR155, TREM2, INPP5D: Disease stage and cell type are essential considerations when targeting clinical interventions based on mouse models of Alzheimer's amyloidopathy

miR155、TREM2、INPP5D:在基于阿尔茨海默病淀粉样变性小鼠模型进行临床干预时,疾病阶段和细胞类型是重要的考虑因素。

Gandy, Sam; Ehrlich, Michelle E

Correction: miR155, TREM2, INPP5D: Disease stage and cell-type are essential considerations when targeting clinical interventions based on mouse models of Alzheimer's amyloidopathy

更正:miR155、TREM2、INPP5D:在基于阿尔茨海默病淀粉样变性小鼠模型进行临床干预时,疾病阶段和细胞类型是重要的考虑因素。

Gandy, Sam; Ehrlich, Michelle E

Effect of Aging and a Dual Orexin Receptor Antagonist on Sleep Architecture and Non-REM Oscillations Including an REM Behavior Disorder Phenotype in the PS19 Mouse Model of Tauopathy.

衰老和双重食欲素受体拮抗剂对睡眠结构和非快速眼动振荡(包括PS19 Tau蛋白病小鼠模型中的快速眼动行为障碍表型)的影响

Kam Korey, Vetter Kenny, Tejiram Rachel A, Pettibone Ward D, Shim Kaitlyn, Audrain Mickael, Yu Liping, Daehn Ilse S, Ehrlich Michelle E, Varga Andrew W