Caspase-1 inhibition by VX-765 administered at reperfusion in P2Y(12) receptor antagonist-treated rats provides long-term reduction in myocardial infarct size and preservation of ventricular function

在P2Y(12)受体拮抗剂治疗的大鼠中，再灌注时给予VX-765抑制caspase-1，可长期减少心肌梗死面积并保护心室功能。