The iron chelator Deferasirox causes severe mitochondrial swelling without depolarization due to a specific effect on inner membrane permeability
由于对内膜通透性有特殊影响,铁螯合剂地拉罗司会导致严重的线粒体肿胀,而不会去极化
期刊:Scientific Reports
影响因子:3.8
doi:10.1038/s41598-020-58386-9
Esther M Gottwald, Claus D Schuh, Patrick Drücker, Dominik Haenni, Adam Pearson, Susan Ghazi, Milica Bugarski, Marcello Polesel, Michael Duss, Ehud M Landau, Andres Kaech, Urs Ziegler, Anne K M Lundby, Carsten Lundby, Petra S Dittrich, Andrew M Hall