日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Phosphorylation of PP2Ac by PKC is a key regulatory step in the PP2A-switch-dependent AKT dephosphorylation that leads to apoptosis

PKC 对 PP2Ac 的磷酸化是 PP2A 开关依赖性 AKT 去磷酸化的关键调节步骤,可导致细胞凋亡

Guy Nadel #, Zhong Yao #, Avital Hacohen-Lev-Ran, Ehud Wainstein, Galia Maik-Rachline, Tamar Ziv, Zvi Naor, Arie Admon, Rony Seger

GqPCR-stimulated dephosphorylation of AKT is induced by an IGBP1-mediated PP2A switch

GqPCR 刺激的 AKT 去磷酸化是由 IGBP1 介导的 PP2A 开关诱导的

Guy Nadel #, Zhong Yao #, Ehud Wainstein #, Izel Cohen, Ido Ben-Ami, Amir Schajnovitz, Galia Maik-Rachline, Zvi Naor, Benjamin A Horwitz, Rony Seger

AKTs do not translocate to the nucleus upon stimulation but AKT3 can constitutively signal from the nuclear envelope

AKT 在受到刺激时不会转位到细胞核,但 AKT3 可以从核膜持续发出信号

Ehud Wainstein, Galia Maik-Rachline, John Blenis, Rony Seger