日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Lung ILC2s are activated in BALB/c mice born to immunized mothers despite complete protection against respiratory syncytial virus

尽管免疫母鼠所产的BALB/c小鼠对呼吸道合胞病毒具有完全保护作用,但其肺部ILC2细胞仍被激活。

Kosanovich, Jessica L; Eichinger, Katherine M; Lipp, Madeline A; Gidwani, Sonal V; Brahmbhatt, Devarshi; Yondola, Mark A; Chi, David H; Perkins, Timothy N; Empey, Kerry M

Targeting cancer metabolic pathways for improving chemotherapy and immunotherapy

靶向癌症代谢通路以改善化疗和免疫疗法

Luo, Zhangyi; Eichinger, Katherine M; Zhang, Anju; Li, Song

Exacerbated lung inflammation following secondary RSV exposure is CD4+ T cell-dependent and is not mitigated in infant BALB/c mice born to PreF-vaccinated dams

二次感染呼吸道合胞病毒后加剧的肺部炎症依赖于 CD4+ T 细胞,并且在接种 PreF 疫苗的母鼠所生的 BALB/c 幼鼠中并未减轻。

Kosanovich, Jessica L; Eichinger, Katherine M; Lipp, Madeline A; Gidwani, Sonal V; Brahmbhatt, Devarshi; Yondola, Mark A; Perkins, Timothy N; Empey, Kerry M

Prior respiratory syncytial virus infection reduces vaccine-mediated Th2-skewed immunity, but retains enhanced RSV F-specific CD8 T cell responses elicited by a Th1-skewing vaccine formulation

既往呼吸道合胞病毒感染会降低疫苗介导的Th2型免疫反应,但仍能维持由Th1型疫苗制剂诱导的增强的RSV F蛋白特异性CD8 T细胞反应。

Eichinger, Katherine M; Kosanovich, Jessica L; Perkins, Timothy N; Oury, Tim D; Petrovsky, Nikolai; Marshall, Christopher P; Yondola, Mark A; Empey, Kerry M

Strategies for active and passive pediatric RSV immunization

儿童呼吸道合胞病毒主动和被动免疫策略

Eichinger, Katherine M; Kosanovich, Jessica L; Lipp, Madeline; Empey, Kerry M; Petrovsky, Nikolai

Prefusion RSV F Immunization Elicits Th2-Mediated Lung Pathology in Mice When Formulated With a Th2 (but Not a Th1/Th2-Balanced) Adjuvant Despite Complete Viral Protection

尽管病毒完全保护,但当使用 Th2 佐剂(而非 Th1/Th2 平衡佐剂)配制融合前 RSV F 免疫时,小鼠仍会诱发 Th2 介导的肺部病理。

Eichinger, Katherine M; Kosanovich, Jessica L; Gidwani, Sonal V; Zomback, Aaron; Lipp, Madeline A; Perkins, Timothy N; Oury, Tim D; Petrovsky, Nikolai; Marshall, Christopher P; Yondola, Mark A; Empey, Kerry M

Maternal immunization with adjuvanted RSV prefusion F protein effectively protects offspring from RSV challenge and alters innate and T cell immunity

母体接种佐剂型呼吸道合胞病毒(RSV)融合前F蛋白可有效保护后代免受RSV感染,并改变先天免疫和T细胞免疫。

Eichinger, Katherine M; Kosanovich, Jessica L; Lipp, Madeline A; Perkins, Timothy N; Petrovsky, Nikolai; Marshall, Christopher; Yondola, Mark A; Empey, Kerry M

Formulation of the prefusion RSV F protein with a Th1/Th2-balanced adjuvant provides complete protection without Th2-skewed immunity in RSV-experienced young mice

将RSV融合前F蛋白与Th1/Th2平衡佐剂配制,可在RSV感染过的幼鼠中提供完全保护,且不会引起Th2型免疫反应。

Kosanovich, Jessica L; Eichinger, Katherine M; Lipp, Madeline A; Yondola, Mark A; Perkins, Timothy N; Empey, Kerry M

Localization of the T-cell response to RSV infection is altered in infant mice

幼鼠体内对呼吸道合胞病毒感染的T细胞反应定位发生改变

Eichinger, Katherine M; Kosanovich, Jessica L; Empey, Kerry M

Age predicts cytokine kinetics and innate immune cell activation following intranasal delivery of IFNγ and GM-CSF in a mouse model of RSV infection

在RSV感染的小鼠模型中,年龄可预测鼻内给予IFNγ和GM-CSF后细胞因子动力学和先天免疫细胞活化情况。

Eichinger, Katherine M; Resetar, Erin; Orend, Jacob; Anderson, Kacey; Empey, Kerry M