Induction of Noxa-mediated apoptosis by modified vaccinia virus Ankara depends on viral recognition by cytosolic helicases, leading to IRF-3/IFN-β-dependent induction of pro-apoptotic Noxa
经修饰的痘苗病毒安卡拉株诱导的Noxa介导的细胞凋亡依赖于胞质解旋酶对病毒的识别,进而导致IRF-3/IFN-β依赖性的促凋亡Noxa蛋白的诱导。
期刊:PLoS Pathogens
影响因子:4.9
doi:10.1371/journal.ppat.1002083
Eitz Ferrer, Pedro; Potthoff, Stephanie; Kirschnek, Susanne; Gasteiger, Georg; Kastenmüller, Wolfgang; Ludwig, Holger; Paschen, Stefan A; Villunger, Andreas; Sutter, Gerd; Drexler, Ingo; Häcker, Georg