日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Reducing Mcl-1 gene dosage induces dopaminergic neuronal loss and motor impairments in Park2 knockout mice

降低 Mcl-1 基因剂量会导致 Park2 基因敲除小鼠的多巴胺能神经元丢失和运动障碍

Susanna Ekholm-Reed, Robert Baker, Alexandre R Campos, David Stouffer, Martha Henze, Dieter A Wolf, Jeanne F Loring, Elizabeth A Thomas, Steven I Reed

Cyclin E deregulation promotes loss of specific genomic regions

细胞周期蛋白E失调促进特定基因组区域的丢失

Teixeira, Leonardo K; Wang, Xianlong; Li, Yongjiang; Ekholm-Reed, Susanna; Wu, Xiaohua; Wang, Pei; Reed, Steven I

Cks overexpression enhances chemotherapeutic efficacy by overriding DNA damage checkpoints

CKS过表达通过绕过DNA损伤检查点来增强化疗疗效

del Rincón, S V; Widschwendter, M; Sun, D; Ekholm-Reed, S; Tat, J; Teixeira, L K; Ellederova, Z; Grolieres, E; Reed, S I; Spruck, C

Parkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1

Parkin 依赖的 F-box 蛋白 Fbw7β 降解可通过稳定 Mcl-1 来促进氧化应激反应中的神经元存活

Susanna Ekholm-Reed, Matthew S Goldberg, Michael G Schlossmacher, Steven I Reed

Fbw7α and Fbw7γ collaborate to shuttle cyclin E1 into the nucleolus for multiubiquitylation

Fbw7α 和 Fbw7γ 协作将细胞周期蛋白 E1 运送到核仁进行多泛素化

Nimesh Bhaskaran, Frank van Drogen, Hwee-Fang Ng, Raman Kumar, Susanna Ekholm-Reed, Matthias Peter, Olle Sangfelt, Steven I Reed

SCFCdc4 acts antagonistically to the PGC-1alpha transcriptional coactivator by targeting it for ubiquitin-mediated proteolysis.

SCFCdc4 通过靶向泛素介导的蛋白水解作用,拮抗 PGC-1α 转录共激活因子

Olson Brian L, Hock M Benjamin, Ekholm-Reed Susanna, Wohlschlegel James A, Dev Kumlesh K, Kralli Anastasia, Reed Steven I

Deregulation of cyclin E in human cells interferes with prereplication complex assembly

人类细胞中细胞周期蛋白E的失调会干扰复制前复合体的组装。

Ekholm-Reed, Susanna; Méndez, Juan; Tedesco, Donato; Zetterberg, Anders; Stillman, Bruce; Reed, Steven I