Rational design, synthesis, and molecular modelling insights of dual DNA binders/DHFR inhibitors bearing arylidene-hydrazinyl-1,3-thiazole scaffold with apoptotic and anti-migratory potential in breast MCF-7 cancer cells.
对具有亚芳基肼基-1,3-噻唑骨架的双重DNA结合剂/DHFR抑制剂进行合理设计、合成和分子建模,以研究其在乳腺癌MCF-7细胞中的凋亡和抗迁移潜力
期刊:Journal of Enzyme Inhibition and Medicinal Chemistry
影响因子:5.4
doi:10.1080/14756366.2025.2468353
El-Wakil Marwa H, Ghazala Rasha A, El-Dershaby Hadeel A, Drozdowska Danuta, Wróbel-TaÅaÅaj Agnieszka, Parzych Cezary, Ratkiewicz Artur, KolesiÅska Beata, Abd El-Razik Heba A, Soliman Farid S G