El-Hashim Ahmed Z相关文献与解析，生知库

Onion bulb extract can both reverse and prevent colitis in mice via inhibition of pro-inflammatory signaling molecules and neutrophil activity

洋葱鳞茎提取物可通过抑制促炎信号分子和中性粒细胞活性，逆转和预防小鼠结肠炎。

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0233938

Khajah, Maitham A; El-Hashim, Ahmed Z; Orabi, Khaled Y; Hawai, Sanaa; Sary, Hanan G

Bradykinin sensitizes the cough reflex via a B(2) receptor dependent activation of TRPV1 and TRPA1 channels through metabolites of cyclooxygenase and 12-lipoxygenase

缓激肽通过环氧合酶和12-脂氧合酶的代谢产物，经由B(2)受体依赖性激活TRPV1和TRPA1通道，从而增强咳嗽反射。

期刊:Respiratory Research

影响因子:5

doi:10.1186/s12931-019-1060-8

Al-Shamlan, Fajer; El-Hashim, Ahmed Z

Ang-(1-7)/ MAS1 receptor axis inhibits allergic airway inflammation via blockade of Src-mediated EGFR transactivation in a murine model of asthma

在哮喘小鼠模型中，Ang-(1-7)/MAS1受体轴通过阻断Src介导的EGFR反式激活来抑制过敏性气道炎症。

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0224163

El-Hashim, Ahmed Z; Khajah, Maitham A; Babyson, Rhema S; Renno, Waleed M; Ezeamuzie, Charles I; Benter, Ibrahim F; Akhtar, Saghir

Central adenosine A(1) receptors inhibit cough via suppression of excitatory glutamatergic and tachykininergic neurotransmission

中枢腺苷A1受体通过抑制兴奋性谷氨酸能和速激肽能神经传递来抑制咳嗽。

期刊:British Journal of Pharmacology

影响因子:7.7

doi:10.1111/bph.14360

El-Hashim, Ahmed Z; Mathews, Seena; Al-Shamlan, Fajer

信号转导

发表日期：2018

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Src-dependent EGFR transactivation regulates lung inflammation via downstream signaling involving ERK1/2, PI3Kδ/Akt and NFκB induction in a murine asthma model

在小鼠哮喘模型中，Src依赖的EGFR反式激活通过下游信号通路（包括ERK1/2、PI3Kδ/Akt和NFκB的诱导）调节肺部炎症。

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-017-09349-0

El-Hashim, Ahmed Z; Khajah, Maitham A; Renno, Waleed M; Babyson, Rhema S; Uddin, Mohib; Benter, Ibrahim F; Ezeamuzie, Charles; Akhtar, Saghir

Cationic Polyamidoamine Dendrimers as Modulators of EGFR Signaling In Vitro and In Vivo.

阳离子聚酰胺胺树状聚合物作为体外和体内 EGFR 信号传导的调节剂

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0132215

Akhtar Saghir, Al-Zaid Bashayer, El-Hashim Ahmed Z, Chandrasekhar Bindu, Attur Sreeja, Yousif Mariam H M, Benter Ibrahim F

Chronic treatment with Ang-(1-7) reverses abnormal reactivity in the corpus cavernosum and normalizes diabetes-induced changes in the protein levels of ACE, ACE2, ROCK1, ROCK2 and omega-hydroxylase in a rat model of type 1 diabetes

在1型糖尿病大鼠模型中，长期使用Ang-(1-7)治疗可逆转阴茎海绵体的异常反应性，并使糖尿病引起的ACE、ACE2、ROCK1、ROCK2和ω-羟化酶蛋白水平的变化恢复正常。

期刊:Journal of Diabetes Research

影响因子:3.4

doi:10.1155/2014/142154

Yousif, Mariam H M; Makki, Batoul; El-Hashim, Ahmed Z; Akhtar, Saghir; Benter, Ibrahim F

Mycobacterium tuberculosis-Specific Antigen Rv3619c Effectively Alleviates Allergic Asthma in Mice

结核分枝杆菌特异性抗原Rv3619c能有效缓解小鼠过敏性哮喘

Onion bulb extract can both reverse and prevent colitis in mice via inhibition of pro-inflammatory signaling molecules and neutrophil activity

洋葱鳞茎提取物可通过抑制促炎信号分子和中性粒细胞活性，逆转和预防小鼠结肠炎。

Bradykinin sensitizes the cough reflex via a B(2) receptor dependent activation of TRPV1 and TRPA1 channels through metabolites of cyclooxygenase and 12-lipoxygenase

缓激肽通过环氧合酶和12-脂氧合酶的代谢产物，经由B(2)受体依赖性激活TRPV1和TRPA1通道，从而增强咳嗽反射。

Ang-(1-7)/ MAS1 receptor axis inhibits allergic airway inflammation via blockade of Src-mediated EGFR transactivation in a murine model of asthma

在哮喘小鼠模型中，Ang-(1-7)/MAS1受体轴通过阻断Src介导的EGFR反式激活来抑制过敏性气道炎症。

Central adenosine A(1) receptors inhibit cough via suppression of excitatory glutamatergic and tachykininergic neurotransmission

中枢腺苷A1受体通过抑制兴奋性谷氨酸能和速激肽能神经传递来抑制咳嗽。

Src-dependent EGFR transactivation regulates lung inflammation via downstream signaling involving ERK1/2, PI3Kδ/Akt and NFκB induction in a murine asthma model

在小鼠哮喘模型中，Src依赖的EGFR反式激活通过下游信号通路（包括ERK1/2、PI3Kδ/Akt和NFκB的诱导）调节肺部炎症。

Cationic Polyamidoamine Dendrimers as Modulators of EGFR Signaling In Vitro and In Vivo.

阳离子聚酰胺胺树状聚合物作为体外和体内 EGFR 信号传导的调节剂

Chronic treatment with Ang-(1-7) reverses abnormal reactivity in the corpus cavernosum and normalizes diabetes-induced changes in the protein levels of ACE, ACE2, ROCK1, ROCK2 and omega-hydroxylase in a rat model of type 1 diabetes

在1型糖尿病大鼠模型中，长期使用Ang-(1-7)治疗可逆转阴茎海绵体的异常反应性，并使糖尿病引起的ACE、ACE2、ROCK1、ROCK2和ω-羟化酶蛋白水平的变化恢复正常。