日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

From Synthesis to Mechanism: Biological Evaluation of a p-Toluidine-Based Thiazolidinone-Quinoline VEGFR-2 Candidate Supported by CADD

从合成到机制:基于对甲苯胺的噻唑烷酮-喹啉类VEGFR-2候选药物的生物学评价(由计算机辅助药物设计提供支持)

Manni, Emad; Hussein, Modather F; Elkady, Sara; Abdel-Rahman, Adel A-H; Hawata, Mohamed A; El-Sayed, Wael A; El-Sayed, Ahmed F; El-Hema, Hagar S

Superiority of Chrysophyllum oliviforme in the green synthesis of highly stable ZnO nanoparticles: metabolomic profiling, quadruple antiviral screening, and comparative MD simulations

金叶蕨在绿色合成高稳定性ZnO纳米颗粒中的优越性:代谢组学分析、四重抗病毒筛选和比较分子动力学模拟

Melk, Mina Michael; El-Sayed, Ahmed F

Design, synthesis, characterization, pharmacological evaluation and in silico ADMET and molecular docking and dynamics simulations of a novel series of N-substituted pyrazole from chalcone derivatives

从查尔酮衍生物出发,设计、合成、表征、药理学评价以及计算机模拟ADMET、分子对接和动力学模拟一系列新型N-取代吡唑化合物

Hafez, Hend N; Otaif, Haleema Y; Alshammari, Basmah H; Alhebshe, Norah S; El-Sayed, Ahmed F; Abbas, Hebat-Allah S; Ammar, Reda A

Design, characterization, DFT studies, and molecular docking of new benzofuran-pyrazol-acrylamide hybrids as insecticidal agents against Spodoptera littoralis and Tribolium castaneum

设计、表征、DFT 研究和分子对接新型苯并呋喃-吡唑-丙烯酰胺杂合物作为防治斜纹夜蛾和赤拟谷盗的杀虫剂

El-Bana, Ghada G; Fouad, Mohamed R; Deeb, Ahmed D H; Wahba, Ahmed M; El-Sayed, Ahmed F; El-Ghani, Ghada E Abd

Unveiling the antibacterial potential of green-synthesized silver chloride and silver chromium nanoparticles from Pelargonium graveolens extract through molecular docking and bioactivity studies

通过分子对接和生物活性研究揭示了从天竺葵提取物中绿色合成的氯化银和银铬纳米粒子的抗菌潜力

Ramadan, Mariam A; Hachem, Zeinab; Abdallah, Alaa M; Ghouch, Nour El; El-Sayed, Ahmed F; Khalil, Mahmoud I; El Hajj, Rana

Cerium oxide nanoparticles attenuate hepatic failure via blocking TGF-β/Smads and upregulating Nrf2/HO-1 signaling pathways in liver fibrosis rat model.

氧化铈纳米颗粒通过阻断 TGF-β/Smads 和上调 Nrf2/HO-1 信号通路来减轻肝纤维化大鼠模型中的肝衰竭。

Mowaad Noha A, Baraka Sara M, Ibrahim Saber, Mansour Doaa A, Korany Reda M S, El-Sayed Ahmed F, Hassan Arwa A

In Vivo Therapeutic Potential of Biologically Synthesized Nanoparticles From Pine Needle Leaf Extract in Streptozotocin-Induced Diabetic Rats

松针叶提取物生物合成纳米颗粒在链脲佐菌素诱导糖尿病大鼠体内的治疗潜力

Darwich, Nourhane A; Abouzeinab, Noura S; El-Sayed, Ahmed F; El Hajj, Rana; Khalil, Mahmoud I

Innovative Amino-Functionalization of Pyrido[2,3-d]pyrimidine Scaffolds for Broad Therapeutic Applications Supported by Computational Analyses

计算分析支持吡啶并[2,3-d]嘧啶骨架的创新氨基功能化及其在广泛治疗应用中的研究

El-Hema, Hagar S; Shehata, Haitham E; Hawata, Mohamed A; Nossier, Eman S; El-Sayed, Ahmed F; Altwaijry, Najla A; Saleh, Asmaa; Hussein, Modather F; Sabry, Amr; Abdel-Rahman, Adel A-H

Design, evaluation, cytotoxic activity, molecular docking, ADMET analysis, and dynamic simulations and the preparation of new isoxazoles, thiazoles, 1,3-thiazines, and thiazolopyrimidines derived from quinoline-pyridopyrimidines.

设计、评价、细胞毒活性、分子对接、ADMET 分析和动态模拟,并制备源自喹啉-吡啶并嘧啶的新型异噁唑、噻唑、1,3-噻嗪和噻唑并嘧啶

Abu-Hashem Ameen A, Amri Nasser, El-Sayed Ahmed F

Enhanced antibacterial and antioxidant capabilities using indole-modified 1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile derivatives, molecular docking evaluation and in silico ADMET prediction

利用吲哚修饰的1-苯基-1H-吡唑并[3,4-b]吡啶-5-腈衍生物增强抗菌和抗氧化能力,进行分子对接评估和计算机模拟ADMET预测

Khalaf, Hemat S; El-Sayed, Ahmed F; Shamroukh, Ahmed H