日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Entrectinib results in ventricular tachycardia and Brugada phenocopy through inhibition of sodium current

恩曲替尼通过抑制钠电流导致室性心动过速和布鲁加达综合征表型。

期刊:Cardiooncology
影响因子:3.2
doi:10.1186/s40959-019-0040-y
Herman, Eugene; Eldridge, Sandy; Fleming, Matthew R; Yang, Tao; Wells, John A; Sunthankar, Kathryn I; Strickland, Teresa L; Blair, Marcia A; Richardson, Travis D; Jahangir, Eiman; Knollmann, Bjorn C; Roden, Dan M
发表日期：2026
文献求助 收藏

Development of a workflow for in vitro on- and off-target cytotoxicity assessment of CAR T cell therapies to support first-in-human clinical trials: An orthogonal approach using human induced pluripotent stem cell-derived cells as a surrogate for normal vital organ systems.

开发用于体外评估 CAR T 细胞疗法靶向和非靶向细胞毒性的工作流程，以支持首次人体临床试验：采用正交方法，利用人类诱导多能干细胞衍生的细胞作为正常重要器官系统的替代物

期刊:Current Research in Toxicology
影响因子:3
doi:10.1016/j.crtox.2025.100243
Price Shari, Zindel Krista G, Overcash Joshua K, Glaze Elizabeth, Eldridge Sandy
发育与干细胞
细胞生物学
Human
发表日期：2025
文献求助 收藏

Validating and Using Cardiac NAMs for Toxicity Screening and Drug Development

验证和利用心脏NAMs进行毒性筛选和药物开发

期刊:International Journal of Toxicology
影响因子:1
doi:10.1177/10915818251375348
Pierson, Jennifer Beck; Bahinski, Anthony; Berridge, Brian; Bramham, Daniel; Bourcier, Todd; Chaudhary, Khuram W; Eldridge, Sandy; Kanda, Yasunari; Mattes, William B; Oliphant, Jessica; Pang, Li; Savtchenko, Alex; Siegel, Jeffery; Simpson, Natalie; Tu, Chengyi; Wange, Ronald; Wu, Joseph C; Yang, Xi
毒理研究
发表日期：2025
文献求助 收藏

Collaborative science in action: A 20 year perspective from the Health and Environmental Sciences Institute (HESI) Cardiac Safety Committee

合作科学实践：来自健康与环境科学研究所（HESI）心脏安全委员会的20年回顾

期刊:Journal of Pharmacological and Toxicological Methods
影响因子:1.8
doi:10.1016/j.vascn.2024.107511
Pierson, Jennifer B; Berridge, Brian; Blinova, Ksenia; Brooks, Marjory B; Eldridge, Sandy; O'Brien, Claire E; Pugsley, Michael K; Schultze, A Eric; Smith, Godfrey; Stockbridge, Norman; Valentin, Jean-Pierre; Vicente, Jose
发表日期：2024
文献求助 收藏

A Comparative Review of Chemotherapy-Induced Peripheral Neuropathy in In Vivo and In Vitro Models

化疗诱导周围神经病变在体内和体外模型中的比较研究

期刊:Toxicologic Pathology
影响因子:1.8
doi:10.1177/0192623319861937
Eldridge, Sandy; Guo, Liang; Hamre, John 3rd
发表日期：2020
文献求助 收藏

Considerations for an In Vitro, Cell-Based Testing Platform for Detection of Drug-Induced Inotropic Effects in Early Drug Development. Part 2: Designing and Fabricating Microsystems for Assaying Cardiac Contractility With Physiological Relevance Using Human iPSC-Cardiomyocytes

体外细胞测试平台在药物早期研发中检测药物诱导正性肌力效应的考量。第二部分：利用人诱导多能干细胞来源的心肌细胞设计和构建具有生理相关性的微系统以检测心脏收缩力

期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2019.00934
Ribeiro, Alexandre J S; Guth, Brian D; Engwall, Michael; Eldridge, Sandy; Foley, C Michael; Guo, Liang; Gintant, Gary; Koerner, John; Parish, Stanley T; Pierson, Jennifer B; Brock, Mathew; Chaudhary, Khuram W; Kanda, Yasunari; Berridge, Brian
细胞生物学
发育与干细胞
Human
干细胞
发表日期：2019
文献求助 收藏

Considerations for an In Vitro, Cell-Based Testing Platform for Detection of Adverse Drug-Induced Inotropic Effects in Early Drug Development. Part 1: General Considerations for Development of Novel Testing Platforms

早期药物研发中用于检测药物诱导的不良正性肌力效应的体外细胞测试平台的考量因素。第一部分：新型测试平台开发的一般性考量因素

期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2019.00884
Guth, Brian D; Engwall, Michael; Eldridge, Sandy; Foley, C Michael; Guo, Liang; Gintant, Gary; Koerner, John; Parish, Stanley T; Pierson, Jennifer B; Ribeiro, Alexandre J S; Zabka, Tanja; Chaudhary, Khuram W; Kanda, Yasunari; Berridge, Brian
细胞生物学
发表日期：2019
文献求助 收藏