Targeting c-MYC and gain-of-function p53 through inhibition or degradation of the kinase LZK suppresses the growth of HNSCC tumors.
通过抑制或降解激酶 LZK 来靶向 c-MYC 和获得功能的 p53，可以抑制 HNSCC 肿瘤的生长
期刊:Science Signaling
影响因子:6.6
doi:10.1126/scisignal.ado2857
Funk Amy L, Katerji Meghri, Afifi Marwa, Nyswaner Katherine, Woodroofe Carolyn C, Edwards Zoe C, Lindberg Eric, Bergman Knickole L, Gough Nancy R, Rubin Maxine R, KarpiÅska Kamila, Trotter Eleanor W, Dash Sweta, Ries Amy L, James Amy, Robinson Christina M, Difilippantonio Simone, Karim Baktiar O, Chang Ting-Chia, Chen Li, Xu Xin, Doroshow James H, Ahel Ivan, Marusiak Anna A, Swenson Rolf E, Cappell Steven D, Brognard John
