An exploratory single-cell analysis of peripheral blood mononuclear cells from vedolizumab-treated Crohn's disease patients identifies response-associated differences among the plasmacytoid dendritic cells and classical monocytes
对接受维多珠单抗治疗的克罗恩病患者外周血单核细胞进行探索性单细胞分析,发现浆细胞样树突状细胞和经典单核细胞之间存在与治疗反应相关的差异。
期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2025.1551017
Li Yim, Andrew Yung Fong; Hageman, Ishtu; Joustra, Vincent W; Elfiky, Ahmed M I M; Ghiboub, Mohammed; Levin, Evgeni; Verhoeff, Jan; Verseijden, Caroline; Admiraal, Iris; de Krijger, Manon; Wildenberg, Manon E; Mannens, Marcel; Jakobs, Marja E; Kenter, Susan B; Adams, Alex T; Satsangi, Jack; D'Haens, Geert R; de Jonge, Wouter J; Henneman, Peter
单细胞
树突状细胞
单核细胞
细胞生物学
克罗恩病
树突状细胞
免疫/内分泌