Microphysiological model of PIK3CA-driven vascular malformations reveals a role of dysregulated Rac1 and mTORC1/2 in lesion formation
PIK3CA 驱动的血管畸形的微生理模型揭示了失调的 Rac1 和 mTORC1/2 在病变形成中的作用
期刊:Science Advances
影响因子:11.7
doi:10.1126/sciadv.ade8939
Wen Yih Aw, Crescentia Cho, Hao Wang, Anne Hope Cooper, Elizabeth L Doherty, David Rocco, Stephanie A Huang, Sarah Kubik, Chloe P Whitworth, Ryan Armstrong, Anthony J Hickey, Boyce Griffith, Matthew L Kutys, Julie Blatt, William J Polacheck